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Table 3 Side-effects: % (n)*

From: Sublingual misoprostol versus standard surgical care for treatment of incomplete abortion in five sub-Saharan African countries

  Misoprostol Surgical p-value
  n = 465 n = 374  
Severity of side effects    
 “None” 14.8 (65/440) 24.0 (53/221) 0.02
 “Easily tolerable” / “tolerable” 77.5 (341/440) 71.0 (157/221)
 “Severe” / “very severe” 7.7 (34/440) 5.0 (11/221)
Normal bleeding** 35.4 (119/336) 9.4 (17/180) < 0.001
Heavy bleeding** 11.6 (39/336) 0.6 (1/180) < 0.001
Spotting*** 31.0 (104/336) 51.1 (92/180) < 0.001
Pain/cramps** 54.8 (184/336) 24.4 (44/180) < 0.001
Fever/chills** 3.9 (13/336) 1.7 (3/180) 0.20
Nausea** 16.7 (56/336) 2.8 (5/180) < 0.001
Vomiting** 7.1 (24/336) 1.1 (2/180) < 0.01
Headache 7.7 (26/336) 8.9 (16/180) 0.74
Gastrointestinal issues 15.2 (51/336) 3.9 (7/180) < 0.001
Vertigo 1.2 (4/336) 4.4 (8/180) 0.03
Tolerability of pain**    
 “No pain” 5.1 (17/332) 5.6 (10/177) < 0.01
 “Very tolerable” / “tolerable” 92.2 (306/332) 85.3 (151/177)
 “Not tolerable” 2.7 (9/332) 9.0 (16/177)
Difficulty of treatment***    0.45
 “Not at all difficult” / “a little difficult” 95.4 (290/304) 97.4 (148/152)
 “Difficult” / “very difficult” 4.6 (14/304) 2.6 (4/152)
Acceptability of bleeding**    
 “Acceptable” / “very acceptable” 99.1 (328/331) 100.0 (174/174) 0.56
 “Not acceptable” 0.9 (3/331) 0.0 (0/0)  
  1. *Denominators vary due to response rate for each question.
  2. **Data only collected in Senegal, Nigeria, and Burkina Faso.
  3. ***Data only collected in Senegal and Burkina Faso.
  4. Listed in “other” side effects; only collected in Senegal, Nigeria, and Burkina Faso.