Table 1 Sample size estimations for the CASTLE study
Exposure ratio (unexposed: exposed) | Outcome of interest | Difference | Sample size estimate |
|---|---|---|---|
Infant no nasal S. aureus /infant nasal S. aureus (1:1) | Mother breast thrush | 5% versus 15% | 318 |
Infant no nasal S. aureus /infant nasal S. aureus (1:1) | Mother mastitis | 12% versus 25% | 308 |
Infant no oral Candida/infant oral Candida (4:1) | Mother breast thrush | 20% versus 50% | 130 |
Infant no oral Candida/infant oral Candida (4:1) | Mother breast thrush | 20% versus 40% | 270 |