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Table 1 Sample size estimations for the CASTLE study

From: The role of micro-organisms (Staphylococcus aureus and Candida albicans) in the pathogenesis of breast pain and infection in lactating women: study protocol

Exposure ratio
(unexposed: exposed)
Outcome of interest Difference Sample size estimate
Infant no nasal S. aureus /infant nasal S. aureus (1:1) Mother breast thrush 5% versus 15% 318
Infant no nasal S. aureus /infant nasal S. aureus (1:1) Mother mastitis 12% versus 25% 308
Infant no oral Candida/infant oral Candida (4:1) Mother breast thrush 20% versus 50% 130
Infant no oral Candida/infant oral Candida (4:1) Mother breast thrush 20% versus 40% 270