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Table 2 GRADE Criteria for Quality of Evidence

From: Global report on preterm birth and stillbirth (3 of 7): evidence for effectiveness of interventions

Quality of Evidence Study Design Interpretation
High Randomized Controlled Trials (RCTs) Further research is very unlikely to change our confidence in the estimate of effect.
Moderate Low-Quality Randomized Trials or High-Quality Observational Studies Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low Observational Studies Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very Low Any Other Evidence Any estimate of effect is very uncertain.