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Table 3 Comparison of clinical outcomes between the control and FCP subgroupsa

From: Diverse impacts of female chromosomal polymorphisms on assisted reproduction outcomes: a retrospective cohort study

 

Rate (cases/study subjects (%))

aRR (95% CI)

Adjusted P value

Biochemical pregnancy

Control

3461/9298(37.2)

Ref.

Ref.

qh+

125/312(40.1)

1.06(0.93 ~ 1.22)

0.389

pstk+

98/269(36.4)

0.97(0.83 ~ 1.14)

0.707

inv(9)

39/100(39.0)

1.02(0.79 ~ 1.30)

0.903

multiple

34/78(43.6)

1.17(0.91 ~ 1.51)

0.212

others

33/74(44.6)

1.17(0.91 ~ 1.50)

0.219

Clinical pregnancy

Control

2861/9298(30.8)

Ref.

Ref.

qh+

104/312(33.3)

1.07(0.91 ~ 1.26)

0.402

pstk+

83/269(30.9)

1.00(0.83 ~ 1.19)

0.957

inv(9)

33/100(33.0)

1.04(0.79 ~ 1.38)

0.789

multiple

26/78(33.3)

1.08(0.79 ~ 1.48)

0.614

others

29/74(39.2)

1.26(0.95 ~ 1.67)

0.113

Miscarriage

Control

951/2861(33.2)

Ref.

Ref.

qh+

25/104(24.0)

0.73(0.52 ~ 1.04)

0.079

pstk+

28/83(33.7)

1.02(0.75 ~ 1.39)

0.890

inv(9)

12/33(36.4)

1.11(0.71 ~ 1.75)

0.650

multiple

8/26(30.8)

0.93(0.52 ~ 1.66)

0.808

others

7/29(24.1)

0.72(0.38 ~ 1.38)

0.325

Preterm birth

Control

291/1772(16.4)

Ref.

Ref.

qh+

12/77(15.6)

0.94(0.55 ~ 1.60)

0.824

pstk+

10/50(20.0)

1.21(0.69 ~ 2.13)

0.512

inv(9)

1/20(5.0)

0.30(0.04 ~ 2.01)

0.212

multiple

5/16(31.3)

1.85(0.89 ~ 3.88)

0.101

others

2/19(10.5)

0.65(0.18 ~ 2.43)

0.524

Live birth

Control

1767/9268(19.1)

Ref.

Ref.

qh+

77/312(24.7)

1.28(1.05 ~ 1.56)

0.014

pstk+

49/269(18.2)

0.95(0.73 ~ 1.22)

0.672

inv(9)

20/100(20.0)

1.02(0.69 ~ 1.51)

0.919

multiple

16/77(20.8)

1.10(0.71 ~ 1.70)

0.663

others

19/73(26.0)

1.37(0.93 ~ 2.01)

0.115

  1. aThe number of couples at each stage was depicted in Fig. 1, while the methods employed for calculation were elucidated in the Materials and Methods Section. Couples who were lost to follow-up were excluded from the calculation of the live birth rate
  2. FCP female chromosomal polymorphism, aRR adjusted risk ratio, CI confidence interval, Ref reference
  3. Log-binomial regression models with adjustment for AFC, diminished ovarian reserve, and paternal factor were employed to calculate the aRRs with their corresponding 95% CIs and adjusted P values
  4. P values less than 0.050 were shown in bold