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Maternal health and pregnancy

This section considers studies regarding all aspects of maternal health during pregnancy, including preeclampsia, gestational diabetes, obesity, anemia, hypertension, alcohol use, and all other aspects of maternal health.

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  1. Women with unplanned pregnancies use folic acid less frequently, and more often use potentially teratogenic medications in the first trimester. Yet most studies based on routinely collected data lack informati...

    Authors: Sarah Hjorth, Mollie Wood, Fatima Tauqeer and Hedvig Nordeng

    Citation: BMC Pregnancy and Childbirth 2020 20:731

    Content type: Research article

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  2. Nowadays, a positive HBV carrier status is common among pregnant women, especially in endemic areas (such as China), little is known about the impact of maternal HBV infection on the risk of adverse pregnancy ...

    Authors: Yulong Zhang, Jiacheng Chen, Tingting Liao, Siwen Chen, Jianying Yan and Xiaoqian Lin

    Citation: BMC Pregnancy and Childbirth 2020 20:724

    Content type: Research article

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    The Correction to this article has been published in BMC Pregnancy and Childbirth 2021 21:131

  3. Hypertensive disorders of pregnancy (HDP) affect 5–10% of pregnant women. Women after HDP have 2–3 times increased risk of heart attack, stroke and diabetes, as soon as 5–10 years after pregnancy. Australian h...

    Authors: Heike Roth, Caroline S. E. Homer, Clare Arnott, Lynne Roberts, Mark Brown and Amanda Henry

    Citation: BMC Pregnancy and Childbirth 2020 20:717

    Content type: Research article

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  4. Our objective was to evaluate risks of adverse obstetric outcomes in pregnancies with myoma(s) or in pregnancies following myomectomy.

    Authors: Se Jin Lee, Hyun Sun Ko, Sunghun Na, Jin Young Bae, Won Joon Seong, Jong Woon Kim, Jaeeun Shin, Hae Joong Cho, Gyu Yeon Choi, Jinsil Kim, Geum Joon Cho and In Yang Park

    Citation: BMC Pregnancy and Childbirth 2020 20:716

    Content type: Research article

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  5. The Medical Birth Registry of Norway (MBRN) provides national coverage of all births. While retrieval of most of the information in the birth records is mandatory, mothers may refrain to provide information on...

    Authors: Liv Grøtvedt, Grace M. Egeland, Liv Grimstvedt Kvalvik and Christian Madsen

    Citation: BMC Pregnancy and Childbirth 2020 20:710

    Content type: Research article

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  6. During pregnancy, about 10 to 20% of women experience depressive symptoms. Subclinical depression increases the risk of peripartum depression, maternal neuro-endocrine dysregulations, and adverse birth and inf...

    Authors: Anke B. Witteveen, Jens Henrichs, Annika L. Walker, Ernst T. Bohlmeijer, Huibert Burger, Yvonne Fontein-Kuipers, Francois G. Schellevis, Claire A.I. Stramrood, Miranda Olff, Corine J. Verhoeven and Ank de Jonge

    Citation: BMC Pregnancy and Childbirth 2020 20:705

    Content type: Study protocol

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  7. There is an unquestionable need to adapt health care to the needs of each woman, to foster her self-confidence and provide her with the autonomy to manage her own maternity. This involves empowering her to cho...

    Authors: Carmen Paz-Pascual, Isabel Artieta-Pinedo, Maite Espinosa and Paola Bully

    Citation: BMC Pregnancy and Childbirth 2020 20:701

    Content type: Study protocol

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  8. The annual rate of stillbirth in Sweden has remained largely unchanged for the past 30 years. In Sweden, there is no national audit system for stillbirths. The aim of the study was to determine if a regional m...

    Authors: I. Sterpu, J. Bolk, S. Perers Öberg, I. Hulthén Varli and E. Wiberg Itzel

    Citation: BMC Pregnancy and Childbirth 2020 20:700

    Content type: Research article

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  9. Full dilatation caesarean sections are associated with recurrent early spontaneous preterm birth and late miscarriage. The risk following first stage caesarean sections, are less well defined, but appears to b...

    Authors: Naomi Carlisle, Agnieszka Glazewska-Hallin, Lisa Story, Jenny Carter, Paul T. Seed, Natalie Suff, Lucie Giblin, Jana Hutter, Raffaele Napolitano, Mary Rutherford, Daniel C. Alexander, Nigel Simpson, Amrita Banerjee, Anna L. David and Andrew H. Shennan

    Citation: BMC Pregnancy and Childbirth 2020 20:698

    Content type: Study protocol

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  10. Under the Children Act 1989, local authorities in Wales, UK, can issue care proceedings if they are concerned about the welfare of a child, which can lead to removal of a child from parents. For mothers at ris...

    Authors: L. J. Griffiths, R. D. Johnson, K. Broadhurst, S. Bedston, L. Cusworth, B. Alrouh, D. V. Ford and A. John

    Citation: BMC Pregnancy and Childbirth 2020 20:697

    Content type: Research article

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  11. The World Health Organization does not recommend dilatation and sharp curettage (D&C) for the surgical treatment of miscarriage during the first trimester because this may cause Asherman’s syndrome due to endo...

    Authors: Toshiyuki Kakinuma, Kaoru Kakinuma, Yuuka Sakamoto, Yoshimasa Kawarai, Koyomi Saito, Motomasa Ihara, Yoshio Matsuda, Ikuo Sato, Michitaka Ohwada, Kaoru Yanagida and Hirokazu Tanaka

    Citation: BMC Pregnancy and Childbirth 2020 20:695

    Content type: Research article

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  12. In 2015, the stillbirth rate after 28 weeks (late gestation) in Australia was 35% higher than countries with the lowest rates globally. Reductions in late gestation stillbirth rates have steadily improved in A...

    Authors: C. J. Andrews, D. Ellwood, P. F. Middleton, A. Gordon, M. Nicholl, C. S. E. Homer, J. Morris, G. Gardener, M. Coory, M. Davies-Tuck, F. M. Boyle, E. Callander, A. Bauman and V. J. Flenady

    Citation: BMC Pregnancy and Childbirth 2020 20:694

    Content type: Study protocol

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  13. Iodine deficiency is the most common cause of preventable brain harm and cognitive impairment in children. Portuguese women of childbearing age, pregnant women and their progeny were shown to have inadequate i...

    Authors: Maria Lopes-Pereira, Susana Roque, Patrício Costa, Anna Quialheiro, Nadine Correia Santos, Ana Goios, Laura Vilarinho, Margarida Correia-Neves and Joana Almeida Palha

    Citation: BMC Pregnancy and Childbirth 2020 20:693

    Content type: Study protocol

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  14. Exposure to environmental stressors can lead to shorter leukocyte telomere length and increase the risk of chronic diseases. Preservation of leukocyte telomere length by reducing oxidative stress exposure and ...

    Authors: Etienne Nsereko, Aline Uwase, Claude Mambo Muvunyi, Stephen Rulisa, David Ntirushwa, Patricia Moreland, Elizabeth J. Corwin, Nicole Santos, Jue Lin, Jyu-Lin Chen, Manasse Nzayirambaho and Janet M. Wojcicki

    Citation: BMC Pregnancy and Childbirth 2020 20:692

    Content type: Research article

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  15. Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic condition characterized by capillary hyperpermeability which can be predicted by preovulatory ovarian responses such as number of follicles. A variety ...

    Authors: Miaad Jabbar Alhilali, Abbas Parham, Armin Attaranzadeh, Malihe Amirian and Mohammad Azizzadeh

    Citation: BMC Pregnancy and Childbirth 2020 20:691

    Content type: Research article

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  16. This study aims to explore the relationships between pre-pregnancy body mass index (BMI), gestational weight gain (GWG), rate of GWG during the second and third trimesters (GWGrate) and birth weight among Chinese...

    Authors: Yawen Wang, Haihui Ma, Yahui Feng, Yongle Zhan, Sansan Wu, Shuya Cai, Yingjie Shi, Yunli Chen, Liangkun Ma and Yu Jiang

    Citation: BMC Pregnancy and Childbirth 2020 20:690

    Content type: Research article

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  17. Propionic acidemia (PA) is a severe monogenic disorder characterized by a deficiency of the mitochondrial protein propionyl-CoA carboxylase (PCC) enzyme, which is caused by mutations in the PCCA or PCCB gene. Pre...

    Authors: Ye Tian, Guojie Wang, Wujuan Shi and Xiaohong Bai

    Citation: BMC Pregnancy and Childbirth 2020 20:689

    Content type: Case report

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  18. Downstream remodeling of the spiral arteries (SpA) decreases utero-placental resistance drastically, allowing sustained and increased blood flow to the placenta under all circumstances. We systematically evalu...

    Authors: Veronique Schiffer, Laura Evers, Sander de Haas, Chahinda Ghossein-Doha, Salwan Al-Nasiry and Marc Spaanderman

    Citation: BMC Pregnancy and Childbirth 2020 20:680

    Content type: Research article

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  19. To date, the rates of potentially life-threatening condition (PTLC), maternal near miss (MNM) and maternal deaths in pregnant patients with type 1 diabetes mellitus (T1DM) and variables associated to it have n...

    Authors: Luiza Russo de Morais, Beatriz Costa Patz, Felipe Favorette Campanharo, Patricia Médici Dualib, Sue Yazaki Sun and Rosiane Mattar

    Citation: BMC Pregnancy and Childbirth 2020 20:679

    Content type: Research article

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  20. The current evidence about anemia and iron deficiency anemia (IDA) during pregnancy remains elusive in China. The purpose of this study is to investigate the prevalence of anemia and IDA and their risk factors...

    Authors: Jing Tan, Guolin He, Yana Qi, Hongmei Yang, Yiquan Xiong, Chunrong Liu, Wen Wang, Kang Zou, Andy H. Lee, Xin Sun and Xinghui Liu

    Citation: BMC Pregnancy and Childbirth 2020 20:670

    Content type: Research article

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  21. The fullPIERS risk prediction model was developed to identify which women admitted with confirmed diagnosis of preeclampsia are at highest risk of developing serious maternal complications. The model discrimin...

    Authors: U. Vivian Ukah, Beth A. Payne, Jennifer A. Hutcheon, Lucy C. Chappell, Paul T. Seed, Frances Inez Conti-Ramsden, J. Mark Ansermino, Laura A. Magee and Peter von Dadelszen

    Citation: BMC Pregnancy and Childbirth 2020 20:668

    Content type: Research article

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  22. Unplanned pregnancy is a significant public health issue in both low- and high-income countries. The burden of unplanned pregnancy is reflected in women opting for pregnancy terminations and it can be detrimen...

    Authors: Iddamalgoda Dissanayakage Jayani Chalindra Ranatunga and Kapila Jayaratne

    Citation: BMC Pregnancy and Childbirth 2020 20:667

    Content type: Research article

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  23. Determination of the optimal timing for termination of pregnancy in cases of preterm premature rupture of membranes (pPROM) during the extremely preterm period is still difficult. Bronchopulmonary dysplasia (B...

    Authors: Eishin Nakamura, Shigetaka Matsunaga, Yoshihisa Ono, Yasushi Takai and Hiroyuki Seki

    Citation: BMC Pregnancy and Childbirth 2020 20:662

    Content type: Research article

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  24. There is strong evidence that women with gestational diabetes mellitus (GDM) who receive a minimum of three appointments with a dietitian may require medication less often. The aim of this study was to evaluat...

    Authors: Nina MELONCELLI, Adrian BARNETT and Susan de JERSEY

    Citation: BMC Pregnancy and Childbirth 2020 20:661

    Content type: Research article

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  25. Antepartum activity restriction (AAR) is a common recommendation given to women at risk for preterm delivery. However, such treatment has been shown to cause heavy emotional burdens on the women receiving it s...

    Authors: Hsiao-Ying Hung, Su-Pin Hung and Ying-Ju Chang

    Citation: BMC Pregnancy and Childbirth 2020 20:659

    Content type: Research article

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  26. The first months postpartum can be challenging for parents, leading to elevated symptoms of parenting stress, depression and anxiety. In turn, distressed parents are at higher risk for providing suboptimal qua...

    Authors: Marjolein Missler, Annemieke van Straten, Jaap Denissen, Tara Donker and Roseriet Beijers

    Citation: BMC Pregnancy and Childbirth 2020 20:658

    Content type: Research article

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  27. HELLP syndrome may increase adverse pregnancy outcomes, though the incidence of it is not high. At present, the impact of HELLP syndrome on P-AKI (acute kidney injury during pregnancy) and maternal and infant ...

    Authors: Qiang Liu, Guan-jun Ling, Shao-quan Zhang, Wen-qing Zhai and Yi-juan Chen

    Citation: BMC Pregnancy and Childbirth 2020 20:657

    Content type: Research article

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  28. Ectopic pregnancy is a major life- and fertility-threatening women’s health concern. As a result of advances in examination technology, an increasing number of ectopic pregnancies can be diagnosed early and tr...

    Authors: Jing Zhang, Yu Zhang, Lu Gan, Xiao-ying Liu and Shan-ping Du

    Citation: BMC Pregnancy and Childbirth 2020 20:654

    Content type: Research article

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  29. Preeclampsia is a severe disease in pregnant women, which is primarily managed by early screening and prevention. Circular RNAs (circRNAs) have increasingly been shown to be important biological regulators inv...

    Authors: Yonggang Zhang, Hongling Yang, Yipeng Zhang, Junzhu Shi and Ronggui Chen

    Citation: BMC Pregnancy and Childbirth 2020 20:652

    Content type: Research article

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  30. Studies investigating the associations of maternal syphilis treatment with birth outcomes mainly concentrated in economically developed areas. Limited data are available in economically underdeveloped areas, s...

    Authors: Zhihua Wan, Huan Zhang, Haigang Xu, Yang Hu, Cai Tan and Yuling Tao

    Citation: BMC Pregnancy and Childbirth 2020 20:648

    Content type: Research article

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  31. Abnormal gestational weight gain (GWG) is a prenatal complication that may contribute to long-term behavioral and neurodevelopmental differences in offspring. This systematic review summarizes research on the ...

    Authors: Sorayya Kheirouri and Mohammad Alizadeh

    Citation: BMC Pregnancy and Childbirth 2020 20:645

    Content type: Research article

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  32. Global investments in neonatal survival have resulted in a growing number of children with morbidities surviving and requiring ongoing care. Little is known about the caregivers of these children in low- and m...

    Authors: Marie Claire Abimana, Egide Karangwa, Ibrahim Hakizimana, Catherine M. Kirk, Kathryn Beck, Ann C. Miller, Silas Havugarurema, Sadallah Bahizi, Alphonsine Uwamahoro, Kim Wilson, Mathieu Nemerimana and Alphonse Nshimyiryo

    Citation: BMC Pregnancy and Childbirth 2020 20:643

    Content type: Research article

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  33. Pregnant women’s exposure to secondhand smoke is a very serious health issue in China. The purpose of our research is to identify factors that predict the probability of exposure to secondhand smoke among preg...

    Authors: Jiangyun Chen, Xinhui Li and Pengqian Fang

    Citation: BMC Pregnancy and Childbirth 2020 20:642

    Content type: Research article

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  34. Evidence-based medicine has shown that successful vaginal birth after cesarean (VBAC) is associated with fewer complications than an elective repeat cesarean. Although spontaneous vaginal births and reductions...

    Authors: Qiuping Liao, Jinying Luo, Lianghui Zheng, Qing Han, Zhaodong Liu, Wei Qi, Tingting Yang and Jianying Yan

    Citation: BMC Pregnancy and Childbirth 2020 20:639

    Content type: Research article

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  35. Observational data from the retrospective, non-randomized Pregnancy REmote MOnitoring I (PREMOM I) study showed that remote monitoring (RM) may be beneficial for prenatal observation of women at risk for gestatio...

    Authors: Dorien Lanssens, Inge M. Thijs and Wilfried Gyselaers

    Citation: BMC Pregnancy and Childbirth 2020 20:626

    Content type: Study protocol

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  36. Preeclampsia/eclampsia is a major cause of maternal morbidity and mortality worldwide, yet patients’ perspectives about their diagnosis are not well understood. Our study examines patient knowledge among women...

    Authors: Avina Joshi, Titus Beyuo, Samuel A. Oppong, Cheryl A. Moyer and Emma R. Lawrence

    Citation: BMC Pregnancy and Childbirth 2020 20:625

    Content type: Research article

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  37. Each day, approximately 810 women die during pregnancy and childbirth and 94% of the deaths take place in low and middle income countries. Only 45% of the births in South Asia are attended by skilled professio...

    Authors: Januka Khatiwada, Basilua Andre Muzembo, Koji Wada and Shunya Ikeda

    Citation: BMC Pregnancy and Childbirth 2020 20:622

    Content type: Research article

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  38. Vitamin D deficiency during pregnancy is common and is likely to be associated with metabolic complications in the mother. The aim of this study was to assess the efficacy of two doses of vitamin D supplementa...

    Authors: Soudabe Motamed, Bahareh Nikooyeh, Maryam Kashanian, Maryam Chamani, Bruce W. Hollis and Tirang R. Neyestani

    Citation: BMC Pregnancy and Childbirth 2020 20:619

    Content type: Research article

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  39. Given the importance of the childbirth experience, its effects on women’s life and society, and the need for its assessment by accurate instruments, this study aimed to determine the psychometric properties of...

    Authors: Mojgan Mirghafourvand, Mohammad Asghari Jafarabadi and Solmaz Ghanbari-Homayi

    Citation: BMC Pregnancy and Childbirth 2020 20:616

    Content type: Research article

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  40. Nearly half of all pregnancies in the United States are reported as unintended and rates are highest among women of low socioeconomic status. The purpose of this study was to examine the associations between u...

    Authors: Alanna M. Cruz-Bendezú, Grace V. Lovell, Brianna Roche, Meghan Perkins, Tiffany L. Blake-Lamb, Elsie M. Taveras and Meg Simione

    Citation: BMC Pregnancy and Childbirth 2020 20:615

    Content type: Research article

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  41. Postpartum depression is considered to be one of the most common health threats during pregnancy and postpartum, affecting not only the woman herself but also the offspring and the whole family system. Evidenc...

    Authors: Alexandra Johann and Ulrike Ehlert

    Citation: BMC Pregnancy and Childbirth 2020 20:609

    Content type: Study protocol

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  42. Women with gestational diabetes mellitus (GDM) have a higher risk of cesarean delivery (CD) than glucose-tolerant women. The aim of this study was to develop and validate a risk score for predicting primary CD...

    Authors: Chadakarn Phaloprakarn and Siriwan Tangjitgamol

    Citation: BMC Pregnancy and Childbirth 2020 20:607

    Content type: Research article

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  43. Low birthweight (LBW) is a significant public health issue, and maternal smoking is the most prevalent preventable cause of LBW. But there is limited evidence on association of LBW among children and cigarette...

    Authors: Ruiping Wang, Ting Sun, Qiong Yang, Qing Yang, Jian Wang, Huan Li, Yue Tang, Liang Yang and Jie Sun

    Citation: BMC Pregnancy and Childbirth 2020 20:603

    Content type: Research article

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  44. Preterm birth (PTB; gestational age < 37 weeks) is the leading cause of infant morbidity and mortality worldwide. Low and excessive gestational weight gain (GWG) have been previously cited as risk factors for ...

    Authors: Stephanie M. Eick, Michael Welton, Mechelle D. Claridy, Skarlet G. Velasquez, Nicholas Mallis and José F. Cordero

    Citation: BMC Pregnancy and Childbirth 2020 20:599

    Content type: Research article

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  45. Although physical activity (PA) in pregnancy benefits most women, not much is known about pregnancy-related changes in PA and its association with gestational diabetes mellitus (GDM) risk. The aim of this stud...

    Authors: Heng Yaw Yong, Zalilah Mohd Shariff, Barakatun Nisak Mohd Yusof, Zulida Rejali, Jacques Bindels, Yvonne Yee Siang Tee and Eline M. van der Beek

    Citation: BMC Pregnancy and Childbirth 2020 20:597

    Content type: Research article

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  46. The management of pregnant women with sickle cell disease (SCD) poses a major challenge for maternal healthcare services owing to the potential for complications associated with morbidity and mortality. Trustw...

    Authors: Yasser S. Amer, Yasser Sabr, Ghada M. ElGohary, Amer M. Altaki, Osamah T. Khojah, Ahmed El-Malky and Musa F. Alzahrani

    Citation: BMC Pregnancy and Childbirth 2020 20:595

    Content type: Research article

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