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Biomedical aspects of pregnancy

This section considers studies regarding biomedical and therapeutic aspects of pregnancy.

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  1. Content type: Research article

    Retinol-binding protein-4 (RBP4) has been reported to be potentially involved in the pathogenesis of gestational diabetes mellitus (GDM); however, the findings are inconsistent. Our aims were to review the stu...

    Authors: Shimin Hu, Qian Liu, Xin Huang and Hongzhuan Tan

    Citation: BMC Pregnancy and Childbirth 2016 16:52

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  2. Content type: Research article

    The dipstick test is widely used as a primary screening test for detection of significant proteinuria in pregnancy (SPIP). However, it often shows a false positive test result. This study was performed to dete...

    Authors: Yosuke Baba, Takahiro Yamada, Mana Obata-Yasuoka, Shun Yasuda, Yasumasa Ohno, Kosuke Kawabata, Shiori Minakawa, Chihiro Hirai, Hideto Kusaka, Nao Murabayashi, Yusuke Inde, Michikazu Nagura, Hiromi Hamada, Atsuo Itakura, Akihide Ohkuchi, Makoto Maeda…

    Citation: BMC Pregnancy and Childbirth 2015 15:331

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  3. Content type: Research article

    The British Columbia Perinatal Data Registry (BCPDR) contains individual-level obstetrical and neonatal medical chart data for virtually all births occurring in British Columbia, Canada. The objective of this ...

    Authors: Gillian Frosst, Jennifer Hutcheon, KS Joseph, Brooke Kinniburgh, Cathe Johnson and Lily Lee

    Citation: BMC Pregnancy and Childbirth 2015 15:123

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  4. Content type: Research article

    Decolonization with topical antibiotics is necessary to control outbreaks of multidrug-resistant bacterial infection in the Neonatal Intensive Care Unit (NICU), but can trigger bacterial resistance. The object...

    Authors: Fernando Lamy Filho, Sílvia Helena Cavalcante de Sousa, Isolina Januária Sousa Freitas, Zeni Carvalho Lamy, Vanda Maria Ferreira Simões, Antônio Augusto Moura da Silva and Marco Antônio Barbieri

    Citation: BMC Pregnancy and Childbirth 2015 15:63

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  5. Content type: Research article

    The development of evidence-based guidelines is a key step in ensuring that maternity care is of a universally high standard. To influence patient care national and international guidelines need to be interpre...

    Authors: Stephanie Jokhan, Melissa K Whitworth, Felicity Jones, Ashleigh Saunders and Alexander E P Heazell

    Citation: BMC Pregnancy and Childbirth 2015 15:54

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  6. Content type: Research article

    Preterm premature rupture of membranes (PPROM) is responsible for one third of all preterm births (PTBs). We have recently demonstrated that long noncoding RNAs (lncRNAs) are differentially expressed in human ...

    Authors: Xiucui Luo, Jing Pan, Leilei Wang, Peirong Wang, Meijiao Zhang, Meilin Liu, Ziqing Dong, Qian Meng, Xuguang Tao, Xinliang Zhao, Julia Zhong, Weina Ju, Yang Gu, Edmund C Jenkins, W Ted Brown, Qingxi Shi…

    Citation: BMC Pregnancy and Childbirth 2015 15:35

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  7. Content type: Research article

    The purpose of this scoping review was to review the literature on healthcare provider provision of anti-D prophylaxis to RhD negative pregnant women in appropriate clinical situations in various healthcare se...

    Authors: Trina M Fyfe, M Jane Ritchey, Christorina Taruc, Daniel Crompton, Brian Galliford and Rose Perrin

    Citation: BMC Pregnancy and Childbirth 2014 14:411

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  8. Content type: Research article

    It is well accepted that the gravid state is hypercoagulable and a significant cause of both maternal morbidity and mortality in the Western world. Although thrombin generation is reported to be increased in p...

    Authors: Jignesh P Patel, Raj K Patel, Lara N Roberts, Michael S Marsh, Bruce Green, J Graham Davies and Roopen Arya

    Citation: BMC Pregnancy and Childbirth 2014 14:384

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  9. Content type: Study protocol

    Antenatal care is of core importance for maternal and child health and is therefore a central aspect of mother and child health care. One of the main goals of effective screening in antenatal care is the detec...

    Authors: Sinja Alexandra Ernst, Anna Reeske, Jacob Spallek, Knud Petersen, Tilman Brand and Hajo Zeeb

    Citation: BMC Pregnancy and Childbirth 2014 14:371

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  10. Content type: Research article

    B7 costimulatory molecules are expressed on antigen presenting cells (APCs) and are important regulators of T cell activation. We investigated the role of the B7 family of costimulatory molecules in the develo...

    Authors: Enikő Grozdics, László Berta, Anna Bajnok, Gábor Veres, István Ilisz, Péter Klivényi, János Rigó Jr, László Vécsei, Tivadar Tulassay and Gergely Toldi

    Citation: BMC Pregnancy and Childbirth 2014 14:306

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  11. Content type: Research article

    Despite the efforts to decrease the rate of preterm birth, preterm delivery is still the main cause of neonatal morbidity and mortality. Identifying patients threatened with preterm delivery remains one of the...

    Authors: Slawomir Wozniak, Piotr Czuczwar, Piotr Szkodziak, Pawel Milart, Ewa Wozniakowska and Tomasz Paszkowski

    Citation: BMC Pregnancy and Childbirth 2014 14:238

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  12. Content type: Study protocol

    The United Kingdom has one of the highest rates of stillbirth in Europe, resulting in approximately 4,000 stillbirths every year. Potentially modifiable risk factors for late stillbirths are maternal age, obes...

    Authors: Jayne Platts, Edwin A Mitchell, Tomasina Stacey, Bill L Martin, Devender Roberts, Lesley McCowan and Alexander E P Heazell

    Citation: BMC Pregnancy and Childbirth 2014 14:171

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  13. Content type: Study protocol

    Improvement in ultrasound imaging has led to the identification of subtle non-structural markers during the 18 – 20 week fetal anomaly scan, such as echogenic bowel, mild cerebral ventriculomegaly, renal pelvi...

    Authors: Lisa Hurt, Melissa Wright, Fiona Brook, Susan Thomas, Frank Dunstan, David Fone, Gareth John, Sue Morris, David Tucker, Marilyn Ann Wills, Lyn Chitty, Colin Davies and Shantini Paranjothy

    Citation: BMC Pregnancy and Childbirth 2014 14:164

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  14. Content type: Erratum

    Authors: Mieke LG ten Eikelder, Femke Neervoort, Katrien Oude Rengerink, Gert J van Baaren, Marta Jozwiak, Jan-Willem de Leeuw, Irene de Graaf, Maria G van Pampus, Maureen Franssen, Martijn Oudijk, Paulien van der Salm, Mallory Woiski, Paula JM Pernet, A Hanneke Feitsma, Huib van Vliet, Martina Porath…

    Citation: BMC Pregnancy and Childbirth 2013 13:183

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    The original article was published in BMC Pregnancy and Childbirth 2013 13:67

  15. Content type: Research article

    The use of the ketogenic diet (KD) among women of child-bearing age has been increasing, leading to increased interest in identifying the diet’s suitability during gestation. To date, no studies have thoroughl...

    Authors: Dafna Sussman, Jacob Ellegood and Mark Henkelman

    Citation: BMC Pregnancy and Childbirth 2013 13:198

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  16. Content type: Research article

    Previous studies carried out in our laboratories have demonstrated impaired drug permeation in diabetic animals. In this study the permeation of diazepam (after a single dose of 5 mg/day, administered intramus...

    Authors: Mladena Lalic-Popovic, Jovana Paunkovic, Zorica Grujic, Svetlana Golocorbin-Kon, Hani Al-Salami and Momir Mikov

    Citation: BMC Pregnancy and Childbirth 2013 13:188

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  17. Content type: Research article

    Nausea and vomiting of pregnancy (NVP) is a common condition. The objective of this study was to evaluate the association between response to antiemetics in the treatment of NVP and genetic polymorphisms in th...

    Authors: Amalia S Lehmann, Jamie L Renbarger, Catherine L McCormick, Ariel R Topletz, Carrie Rouse and David M Haas

    Citation: BMC Pregnancy and Childbirth 2013 13:132

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  18. Content type: Research article

    Lactate dehydrogenase (LDH) isoenzymes are required for adenosine triphosphate production, with each of five different isoenzymes having varying proficiencies in anaerobic versus aerobic environments. With adv...

    Authors: Jeremy L Neal, Nancy K Lowe and Elizabeth J Corwin

    Citation: BMC Pregnancy and Childbirth 2013 13:128

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  19. Content type: Research article

    Many clinicians and hepatitis B virus (HBV)-infected pregnant women prefer elective caesarean section (ECS) to prevent mother-to-child transmission of HBV, since some studies found higher transmission of HBV i...

    Authors: Yali Hu, Jie Chen, Jian Wen, Chenyu Xu, Shu Zhang, Biyun Xu and Yi-Hua Zhou

    Citation: BMC Pregnancy and Childbirth 2013 13:119

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