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Biomedical aspects of pregnancy

This section considers studies regarding biomedical and therapeutic aspects of pregnancy.

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  1. Content type: Study protocol

    Antenatal care is of core importance for maternal and child health and is therefore a central aspect of mother and child health care. One of the main goals of effective screening in antenatal care is the detec...

    Authors: Sinja Alexandra Ernst, Anna Reeske, Jacob Spallek, Knud Petersen, Tilman Brand and Hajo Zeeb

    Citation: BMC Pregnancy and Childbirth 2014 14:371

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  2. Content type: Research article

    B7 costimulatory molecules are expressed on antigen presenting cells (APCs) and are important regulators of T cell activation. We investigated the role of the B7 family of costimulatory molecules in the develo...

    Authors: Enikő Grozdics, László Berta, Anna Bajnok, Gábor Veres, István Ilisz, Péter Klivényi, János Rigó Jr, László Vécsei, Tivadar Tulassay and Gergely Toldi

    Citation: BMC Pregnancy and Childbirth 2014 14:306

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  3. Content type: Research article

    Despite the efforts to decrease the rate of preterm birth, preterm delivery is still the main cause of neonatal morbidity and mortality. Identifying patients threatened with preterm delivery remains one of the...

    Authors: Slawomir Wozniak, Piotr Czuczwar, Piotr Szkodziak, Pawel Milart, Ewa Wozniakowska and Tomasz Paszkowski

    Citation: BMC Pregnancy and Childbirth 2014 14:238

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  4. Content type: Study protocol

    The United Kingdom has one of the highest rates of stillbirth in Europe, resulting in approximately 4,000 stillbirths every year. Potentially modifiable risk factors for late stillbirths are maternal age, obes...

    Authors: Jayne Platts, Edwin A Mitchell, Tomasina Stacey, Bill L Martin, Devender Roberts, Lesley McCowan and Alexander E P Heazell

    Citation: BMC Pregnancy and Childbirth 2014 14:171

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  5. Content type: Study protocol

    Improvement in ultrasound imaging has led to the identification of subtle non-structural markers during the 18 – 20 week fetal anomaly scan, such as echogenic bowel, mild cerebral ventriculomegaly, renal pelvi...

    Authors: Lisa Hurt, Melissa Wright, Fiona Brook, Susan Thomas, Frank Dunstan, David Fone, Gareth John, Sue Morris, David Tucker, Marilyn Ann Wills, Lyn Chitty, Colin Davies and Shantini Paranjothy

    Citation: BMC Pregnancy and Childbirth 2014 14:164

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  6. Content type: Erratum

    Authors: Mieke LG ten Eikelder, Femke Neervoort, Katrien Oude Rengerink, Gert J van Baaren, Marta Jozwiak, Jan-Willem de Leeuw, Irene de Graaf, Maria G van Pampus, Maureen Franssen, Martijn Oudijk, Paulien van der Salm, Mallory Woiski, Paula JM Pernet, A Hanneke Feitsma, Huib van Vliet, Martina Porath…

    Citation: BMC Pregnancy and Childbirth 2013 13:183

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    The original article was published in BMC Pregnancy and Childbirth 2013 13:67

  7. Content type: Research article

    The use of the ketogenic diet (KD) among women of child-bearing age has been increasing, leading to increased interest in identifying the diet’s suitability during gestation. To date, no studies have thoroughl...

    Authors: Dafna Sussman, Jacob Ellegood and Mark Henkelman

    Citation: BMC Pregnancy and Childbirth 2013 13:198

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  8. Content type: Research article

    Previous studies carried out in our laboratories have demonstrated impaired drug permeation in diabetic animals. In this study the permeation of diazepam (after a single dose of 5 mg/day, administered intramus...

    Authors: Mladena Lalic-Popovic, Jovana Paunkovic, Zorica Grujic, Svetlana Golocorbin-Kon, Hani Al-Salami and Momir Mikov

    Citation: BMC Pregnancy and Childbirth 2013 13:188

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  9. Content type: Research article

    Nausea and vomiting of pregnancy (NVP) is a common condition. The objective of this study was to evaluate the association between response to antiemetics in the treatment of NVP and genetic polymorphisms in th...

    Authors: Amalia S Lehmann, Jamie L Renbarger, Catherine L McCormick, Ariel R Topletz, Carrie Rouse and David M Haas

    Citation: BMC Pregnancy and Childbirth 2013 13:132

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  10. Content type: Research article

    Lactate dehydrogenase (LDH) isoenzymes are required for adenosine triphosphate production, with each of five different isoenzymes having varying proficiencies in anaerobic versus aerobic environments. With adv...

    Authors: Jeremy L Neal, Nancy K Lowe and Elizabeth J Corwin

    Citation: BMC Pregnancy and Childbirth 2013 13:128

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  11. Content type: Research article

    Many clinicians and hepatitis B virus (HBV)-infected pregnant women prefer elective caesarean section (ECS) to prevent mother-to-child transmission of HBV, since some studies found higher transmission of HBV i...

    Authors: Yali Hu, Jie Chen, Jian Wen, Chenyu Xu, Shu Zhang, Biyun Xu and Yi-Hua Zhou

    Citation: BMC Pregnancy and Childbirth 2013 13:119

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  12. Content type: Study protocol

    Medical treatment with misoprostol is a non-invasive and inexpensive treatment option in first trimester miscarriage. However, about 30% of women treated with misoprostol have incomplete evacuation of the uter...

    Authors: Marianne AC Verschoor, Marike Lemmers, Patrick M Bossuyt, Giuseppe CM Graziosi, Petra J Hajenius, Dave J Hendriks, Marcel AH van Hooff, Hannah S van Meurs, Brent C Opmeer, Maurits W van Tulder, Liesanne Bouwma, Ruby Catshoek, Peggy Geomini, Ellen R Klinkert, Josje Langenveld, Theodoor E Nieboer…

    Citation: BMC Pregnancy and Childbirth 2013 13:102

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  13. Content type: Research article

    Severe perineal trauma occurs in 0.5-10% of vaginal births and can result in significant morbidity including pain, dyspareunia and faecal incontinence. The aim of this study is to determine the risk of recurre...

    Authors: Holly Priddis, Hannah G Dahlen, Virginia Schmied, Annie Sneddon, Christine Kettle, Chris Brown and Charlene Thornton

    Citation: BMC Pregnancy and Childbirth 2013 13:89

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  14. Content type: Study protocol

    Induction of labour is a common obstetric procedure. At present, different methods are used for induction of labour in women with an unfavourable cervix. Recently, we showed that in term women with an unfavora...

    Authors: Mieke LG ten Eikelder, Femke Neervoort, Katrien Oude Rengerink, Marta Jozwiak, Jan-Willem de Leeuw, Irene de Graaf, Maria G van Pampus, Maureen Franssen, Martijn Oudijk, Paulien van der Salm, Mallory Woiski, Paula JM Pernet, A Hanneke Feitsma, Huib van Vliet, Martina Porath, Frans Roumen…

    Citation: BMC Pregnancy and Childbirth 2013 13:67

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    The Erratum to this article has been published in BMC Pregnancy and Childbirth 2013 13:183

  15. Content type: Research article

    Active management of the third stage of labor is recommended for the prevention of post-partum hemorrhage and commonly entails prophylactic administration of a uterotonic agent, controlled cord traction, and u...

    Authors: Wendy R Sheldon, Jill Durocher, Beverly Winikoff, Jennifer Blum and James Trussell

    Citation: BMC Pregnancy and Childbirth 2013 13:46

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  16. Content type: Research article

    Vaginal delivery after previous one cesarean section for a non recurring indication has been described by several authors as safe and having a success rate of 60–80%. Hence many centers are offering VBAC for c...

    Authors: Malede Birara and Yirgu Gebrehiwot

    Citation: BMC Pregnancy and Childbirth 2013 13:31

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  17. Content type: Research article

    The current measure of treatment efficacy of single-dose methotrexate for ectopic pregnancy, is a fall in serum hCG of ≥15% between days 4–7 of treatment, which has a positive predictive value of 93% for treat...

    Authors: Monika Skubisz, Philip Dutton, William Colin Duncan, Andrew W Horne and Stephen Tong

    Citation: BMC Pregnancy and Childbirth 2013 13:30

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  18. Content type: Research article

    The modern phenomenon of delayed parenthood applies not only to women but also to men, but less is known about what characterises men who are expecting their first child at an advanced age. This study investig...

    Authors: Anne Britt Vika Nilsen, Ulla Waldenström, Svein Rasmussen, Anna Hjelmstedt and Erica Schytt

    Citation: BMC Pregnancy and Childbirth 2013 13:29

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  19. Content type: Research article

    Induction of labour (IOL) is one of the commonest obstetric interventions, with significant impact on both the individual woman and health service delivery. Outpatient IOL is an attractive option to reduce the...

    Authors: Amanda Henry, Arushi Madan, Rachel Reid, Sally K Tracy, Kathryn Austin, Alec Welsh and Daniel Challis

    Citation: BMC Pregnancy and Childbirth 2013 13:25

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