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BMC Pregnancy and Childbirth

Biomedical aspects of pregnancy

This section considers studies regarding biomedical and therapeutic aspects of pregnancy.

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  1. Content type: Study protocol

    The fetal anomaly ultrasound only detects 65 to 81 % of the patients with congenital heart disease, making it the most common structural fetal anomaly of which a significant part is missed during prenatal life...

    Authors: Kim M. J. Verdurmen, Carlijn Lempersz, Rik Vullings, Christian Schroer, Tammo Delhaas, Judith O. E. H. van Laar and S. Guid Oei

    Citation: BMC Pregnancy and Childbirth 2016 16:227

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  2. Content type: Study protocol

    Spontaneous preterm birth is a complex syndrome with multiple pathways interactions determining its occurrence, including genetic, immunological, physiologic, biochemical and environmental factors. Despite gre...

    Authors: Jose G. Cecatti, Renato T. Souza, Karolina Sulek, Maria L. Costa, Louise C. Kenny, Lesley M. McCowan, Rodolfo C. Pacagnella, Silas G. Villas-Boas, Jussara Mayrink, Renato Passini Jr, Kleber G. Franchini and Philip N. Baker

    Citation: BMC Pregnancy and Childbirth 2016 16:212

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  3. Content type: Research article

    Adiponectin is an adipocyte hormone involved in energy homeostasis and metabolism. However, its role in early infancy is poorly understood.

    Authors: Zhe-qing Zhang, Qing-gui Lu, Jie Huang, Chang-ya Jiao, Shao-ming Huang and Li-mei Mao

    Citation: BMC Pregnancy and Childbirth 2016 16:189

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  4. Content type: Research article

    Evidence suggests that the hormonal milieu of pregnancy is an important determinant of subsequent cancer and other chronic diseases in both the mother and the offspring. Many of the existing maternity and birt...

    Authors: Helena Schock, Anne Zeleniuch-Jacquotte, Eva Lundin, Kjell Grankvist, Hans-Åke Lakso, Annika Idahl, Matti Lehtinen, Heljä-Marja Surcel and Renée T. Fortner

    Citation: BMC Pregnancy and Childbirth 2016 16:146

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  5. Content type: Research article

    Prenatal cardiac screening is of great importance as it contributes to appropriate neonatal management and helps parents to make a decision regarding their pregnancy. The aim of our study was to evaluate the e...

    Authors: Ying Zhang, Ai-Lu Cai, Wei-dong Ren, Ya-Jun Guo, Dong-yu Zhang, Wei Sun, Yu Wang, Lei Wang, Yue Qin and Li-ping Huang

    Citation: BMC Pregnancy and Childbirth 2016 16:145

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  6. Content type: Research article

    Perinatal depression has a significant impact on both mother and child. However, the influence of hormonal changes during pregnancy and the postpartum period remains unclear. This article provides a systematic...

    Authors: Sunaina Seth, Andrew J. Lewis and Megan Galbally

    Citation: BMC Pregnancy and Childbirth 2016 16:124

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  7. Content type: Research article

    Preeclampsia is associated with the placental release of soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG). These anti-angiogenic factors cause hypertension and multi-organ injury. Pravas...

    Authors: Fiona C. Brownfoot, Stephen Tong, Natalie J. Hannan, Roxanne Hastie, Ping Cannon and Tu’uhevaha J. Kaitu’u-Lino

    Citation: BMC Pregnancy and Childbirth 2016 16:117

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  8. Content type: Research article

    Gradual increases in mass such as during pregnancy are associated with changes in gait at natural velocities. The purpose of this study was to examine how added mass at natural and imposed slow walking velocit...

    Authors: Simone V. Gill, Maureen Ogamba and Cara L. Lewis

    Citation: BMC Pregnancy and Childbirth 2016 16:109

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  9. Content type: Research article

    Retinol-binding protein-4 (RBP4) has been reported to be potentially involved in the pathogenesis of gestational diabetes mellitus (GDM); however, the findings are inconsistent. Our aims were to review the stu...

    Authors: Shimin Hu, Qian Liu, Xin Huang and Hongzhuan Tan

    Citation: BMC Pregnancy and Childbirth 2016 16:52

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  10. Content type: Research article

    The dipstick test is widely used as a primary screening test for detection of significant proteinuria in pregnancy (SPIP). However, it often shows a false positive test result. This study was performed to dete...

    Authors: Yosuke Baba, Takahiro Yamada, Mana Obata-Yasuoka, Shun Yasuda, Yasumasa Ohno, Kosuke Kawabata, Shiori Minakawa, Chihiro Hirai, Hideto Kusaka, Nao Murabayashi, Yusuke Inde, Michikazu Nagura, Hiromi Hamada, Atsuo Itakura, Akihide Ohkuchi, Makoto Maeda…

    Citation: BMC Pregnancy and Childbirth 2015 15:331

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  11. Content type: Research article

    The British Columbia Perinatal Data Registry (BCPDR) contains individual-level obstetrical and neonatal medical chart data for virtually all births occurring in British Columbia, Canada. The objective of this ...

    Authors: Gillian Frosst, Jennifer Hutcheon, KS Joseph, Brooke Kinniburgh, Cathe Johnson and Lily Lee

    Citation: BMC Pregnancy and Childbirth 2015 15:123

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  12. Content type: Research article

    Decolonization with topical antibiotics is necessary to control outbreaks of multidrug-resistant bacterial infection in the Neonatal Intensive Care Unit (NICU), but can trigger bacterial resistance. The object...

    Authors: Fernando Lamy Filho, Sílvia Helena Cavalcante de Sousa, Isolina Januária Sousa Freitas, Zeni Carvalho Lamy, Vanda Maria Ferreira Simões, Antônio Augusto Moura da Silva and Marco Antônio Barbieri

    Citation: BMC Pregnancy and Childbirth 2015 15:63

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  13. Content type: Research article

    The development of evidence-based guidelines is a key step in ensuring that maternity care is of a universally high standard. To influence patient care national and international guidelines need to be interpre...

    Authors: Stephanie Jokhan, Melissa K Whitworth, Felicity Jones, Ashleigh Saunders and Alexander E P Heazell

    Citation: BMC Pregnancy and Childbirth 2015 15:54

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  14. Content type: Research article

    Preterm premature rupture of membranes (PPROM) is responsible for one third of all preterm births (PTBs). We have recently demonstrated that long noncoding RNAs (lncRNAs) are differentially expressed in human ...

    Authors: Xiucui Luo, Jing Pan, Leilei Wang, Peirong Wang, Meijiao Zhang, Meilin Liu, Ziqing Dong, Qian Meng, Xuguang Tao, Xinliang Zhao, Julia Zhong, Weina Ju, Yang Gu, Edmund C Jenkins, W Ted Brown, Qingxi Shi…

    Citation: BMC Pregnancy and Childbirth 2015 15:35

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  15. Content type: Research article

    The purpose of this scoping review was to review the literature on healthcare provider provision of anti-D prophylaxis to RhD negative pregnant women in appropriate clinical situations in various healthcare se...

    Authors: Trina M Fyfe, M Jane Ritchey, Christorina Taruc, Daniel Crompton, Brian Galliford and Rose Perrin

    Citation: BMC Pregnancy and Childbirth 2014 14:411

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  16. Content type: Research article

    It is well accepted that the gravid state is hypercoagulable and a significant cause of both maternal morbidity and mortality in the Western world. Although thrombin generation is reported to be increased in p...

    Authors: Jignesh P Patel, Raj K Patel, Lara N Roberts, Michael S Marsh, Bruce Green, J Graham Davies and Roopen Arya

    Citation: BMC Pregnancy and Childbirth 2014 14:384

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  17. Content type: Study protocol

    Antenatal care is of core importance for maternal and child health and is therefore a central aspect of mother and child health care. One of the main goals of effective screening in antenatal care is the detec...

    Authors: Sinja Alexandra Ernst, Anna Reeske, Jacob Spallek, Knud Petersen, Tilman Brand and Hajo Zeeb

    Citation: BMC Pregnancy and Childbirth 2014 14:371

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  18. Content type: Research article

    B7 costimulatory molecules are expressed on antigen presenting cells (APCs) and are important regulators of T cell activation. We investigated the role of the B7 family of costimulatory molecules in the develo...

    Authors: Enikő Grozdics, László Berta, Anna Bajnok, Gábor Veres, István Ilisz, Péter Klivényi, János Rigó Jr, László Vécsei, Tivadar Tulassay and Gergely Toldi

    Citation: BMC Pregnancy and Childbirth 2014 14:306

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  19. Content type: Research article

    Despite the efforts to decrease the rate of preterm birth, preterm delivery is still the main cause of neonatal morbidity and mortality. Identifying patients threatened with preterm delivery remains one of the...

    Authors: Slawomir Wozniak, Piotr Czuczwar, Piotr Szkodziak, Pawel Milart, Ewa Wozniakowska and Tomasz Paszkowski

    Citation: BMC Pregnancy and Childbirth 2014 14:238

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  20. Content type: Study protocol

    The United Kingdom has one of the highest rates of stillbirth in Europe, resulting in approximately 4,000 stillbirths every year. Potentially modifiable risk factors for late stillbirths are maternal age, obes...

    Authors: Jayne Platts, Edwin A Mitchell, Tomasina Stacey, Bill L Martin, Devender Roberts, Lesley McCowan and Alexander E P Heazell

    Citation: BMC Pregnancy and Childbirth 2014 14:171

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