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Biomedical aspects of pregnancy

This section considers studies regarding biomedical and therapeutic aspects of pregnancy.

Page 1 of 3

  1. The purpose of this research is to summarize the prenatal ultrasound characteristics of congenital duodenal obstruction (CDO), especially in the diagnosis of duodenal diaphragm and annular pancreas. At present...

    Authors: Chan Yin, Lili Tong, Mingxiang Ma, Xiaoqun Tan, Guoliang Luo, Zhihui Fei and Dan Nie

    Citation: BMC Pregnancy and Childbirth 2020 20:387

    Content type: Research article

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  2. There has been debate about the existence of lymphatic vessels in placenta. Lymphatic endothelial cell (LEC) markers such as LYVE-1 and podoplanin/D2–40 have been found, although PROX1 has not been detected. T...

    Authors: Jürgen Becker, Gilles E. Tchagou Tchangou, Sonja Schmidt, Christina Zelent, Fritz Kahl and Jörg Wilting

    Citation: BMC Pregnancy and Childbirth 2020 20:380

    Content type: Research article

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  3. Gestational diabetes mellitus (GDM) is associated with adverse diabetic complications for both mother and child during pregnancy. The common Gold Standard (GS) for diagnosis of GDM is 75 g oral glucose toleran...

    Authors: Maedeh Amini, Anoshirvan Kazemnejad, Farid Zayeri, Ali Montazeri, Aliakbar Rasekhi, Azam Amirian and Nourossadat Kariman

    Citation: BMC Pregnancy and Childbirth 2020 20:375

    Content type: Research article

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  4. A high incidence of posterior reversible encephalopathy syndrome (PRES) has been observed in women with eclampsia on imaging. However this association was documented mostly after convulsions occurred. This stu...

    Authors: An-Shine Chao, Yao-Liang Chen, Yao-Lung Chang, Angel Chao, Seng-Yuan Su and Tzu-Hao Wang

    Citation: BMC Pregnancy and Childbirth 2020 20:336

    Content type: Research article

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  5. Many studies have demonstrated the benefits of the addition of growth hormone (GH) to the controlled ovarian stimulation protocol in vitro fertilization (IVF) cycles in poor-respond patients, but the effect of...

    Authors: Jingyu Li, Qiaoli Chen, Jiang Wang, Guoning Huang and Hong Ye

    Citation: BMC Pregnancy and Childbirth 2020 20:310

    Content type: Research article

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  6. Candida is the leading cause of vaginitis, and 75% of women have at least one episode of infection in their lives, with pregnancy being a predisposing factor. If left untreated, vulvovaginal candidiasis (VVC) can...

    Authors: Sayanika Devi Waikhom, Innocent Afeke, Grace Sefakor Kwawu, Hintermann Kobina Mbroh, George Yiadom Osei, Bengyella Louis, John Gameli Deku, Emmanuel Senyo Kasu, Prosper Mensah, Charles Yao Agede, Cornelius Dodoo, Emmanuel Akomanin Asiamah, John Tampuori, John Korbuvi and Japheth Awuletey Opintan

    Citation: BMC Pregnancy and Childbirth 2020 20:266

    Content type: Research article

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  7. Probiotic supplementation has been shown to be beneficial and is now widely promoted as an auxiliary medicine for maternal health, but the underlying mechanism is still unclear. Thus, this study aimed to explo...

    Authors: Ping Yang, Zhe Li, Kian Deng Tye, Yuyi Chen, Tong Lu, Zonglin He, Juan Zhou and Xiaomin Xiao

    Citation: BMC Pregnancy and Childbirth 2020 20:216

    Content type: Research article

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  8. Both follicle stimulating hormone (FSH) and anti-mullerian hormone (AMH) are widely used to assess the ovarian reserve in women for in vitro fertilization (IVF). However, studies also showed that both AMH and ...

    Authors: Han-Chih Hsieh, Jia-Ying Su, Shunping Wang and Yen-Tsung Huang

    Citation: BMC Pregnancy and Childbirth 2020 20:209

    Content type: Research Article

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  9. Geophagia although pleasurable and somewhat a necessity among pregnant women, also comes along with its own attendant problems such as exposure to potentially hazardous substances like bacteria, fungi, helmint...

    Authors: Nii Korley Kortei, Alice Koryo-Dabrah, Papa Toah Akonor, Nana Yaw Barimah Manaphraim, Matilda Ayim-Akonor, Nathaniel Owusu Boadi, Edward Ken Essuman and Clement Tettey

    Citation: BMC Pregnancy and Childbirth 2020 20:160

    Content type: Research article

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  10. Currently, there are many studies researched the associations between maternal serum inflammatory indicators (i.e. ferritin, C-reactive protein [CRP], C3 and C4) and preterm birth (PTB). The results, however, ...

    Authors: Shengzhu Huang, Jiarong Tian, Chaoqun Liu, Yu Long, Dehao Cao, Luyun Wei, Xiujuan Zhu, Ruiqiang Tang, Weiwu Liu, Dingyuan Zeng, Mujun Li, Xiaobo Yang and Zengnan Mo

    Citation: BMC Pregnancy and Childbirth 2020 20:131

    Content type: Research article

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  11. Non-obstetric surgery conducted during pregnancy may increase the risk of adverse birth outcomes like small for gestational age, preterm birth, and miscarriage. Mechanisms are unclear but possibly longer lasti...

    Authors: Anne Staub Rasmussen, Christian Fynbo Christiansen, Niels Uldbjerg and Mette Nørgaard

    Citation: BMC Pregnancy and Childbirth 2020 20:108

    Content type: Research article

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  12. It is well known that second-trimester maternal serum alpha-fetoprotein (MS-AFP) is a predictor for adverse pregnancy outcomes (APOs), such as preterm birth, stillbirth, preeclampsia and small for gestational ...

    Authors: Jilin Hu, Jinman Zhang, Guilin He, Shu Zhu, Xinhua Tang, Jie Su, Qian Li, Yamin Kong and Baosheng Zhu

    Citation: BMC Pregnancy and Childbirth 2020 20:104

    Content type: Research article

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  13. CXCL12(chemokine ligand 12, CXCL12) and its receptors CXCR4 are widely expressed in maternal-fetal interface and plays an adjust role in materno-fetal dialogue and immune tolerance during early pregnancy. This...

    Authors: Jiayi Zheng, Danni Qu, Chen Wang, Ling Ding and Wenhui Zhou

    Citation: BMC Pregnancy and Childbirth 2020 20:87

    Content type: Research article

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  14. Gestational diabetes mellitus (GDM) is a growing global epidemic. Our study aims to confirm the association between circulatory coiled-coil domain-containing 80 (CCDC80) in pregnant women with GDM, to investig...

    Authors: Lei Liu, Jiajin Hu, Ningning Wang, Yang Liu, Xiaotong Wei, Ming Gao, Yanan Ma and Deliang Wen

    Citation: BMC Pregnancy and Childbirth 2020 20:53

    Content type: Research article

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  15. Many efforts have been focused on the alternative glycemic marker glycated albumin (GlyA) and its application in pregnancy during which profound physiological changes take place. Our objective was to determine...

    Authors: Ying Dong, Yanhong Zhai, Jing Wang, Yi Chen, Xin Xie, Chunhong Zhang, Jingrui Liu, Yifan Lu, Guodong Tang, Lican Han, Lin Li and Zheng Cao

    Citation: BMC Pregnancy and Childbirth 2020 20:12

    Content type: Research article

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  16. Premature birth is the main cause of mortality in children under 1 year, and vitamin D deficiency during gestation is associated with prematurity. The effects of vitamin D are mediated by its receptor, which i...

    Authors: Letícia Veríssimo Dutra, Fernando Alves Affonso-Kaufman, Fernanda Ramires Cafeo, Milene Saori Kassai, Caio Parente Barbosa, Francisco Winter Santos Figueiredo, Fabíola Isabel Suano-Souza and Bianca Bianco

    Citation: BMC Pregnancy and Childbirth 2019 20:3

    Content type: Research article

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  17. Group B Streptococcus (GBS) is one of the most important causative agents of neonatal sepsis. As administration of prophylactic antibiotics during labor can prevent GBS infection, routine screening for this bacte...

    Authors: Laura L. Vieira, Amanda V. Perez, Monique M. Machado, Michele L. Kayser, Daniela V. Vettori, Ana Paula Alegretti, Charles F. Ferreira, Janete Vettorazzi and Edimárlei G. Valério

    Citation: BMC Pregnancy and Childbirth 2019 19:532

    Content type: Research article

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  18. Candida is the commonest opportunistic fungi in human. Candida species cause diverse types of diseases. Vaginal candidiasis has been reported as one of the most common type of fungal diseases among pregnant women...

    Authors: Alem Tsega and Feleke Mekonnen

    Citation: BMC Pregnancy and Childbirth 2019 19:527

    Content type: Research article

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  19. Myocardial deformation imaging offers the potential to measure myocardial function. Remodelling, the change in size, shape and function, appears as a result of pressure or volume changes and is thought to be t...

    Authors: Noortje H. M. van Oostrum, S. Guid Oei and Judith O. E. H. van Laar

    Citation: BMC Pregnancy and Childbirth 2019 19:524

    Content type: Study protocol

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  20. Pregnancy management in women with Wilson disease (WD) remains an important clinical problem. This research was conducted to investigate how to avoid worsening of WD symptoms during pregnancy and increase preg...

    Authors: Xu-En Yu, Min Pan, Yong-Zhu Han, Ren-Min Yang, Juan Wang and Shan Gao

    Citation: BMC Pregnancy and Childbirth 2019 19:522

    Content type: Research article

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  21. Antenatal depression affects 10–20% of pregnant women. Around 2–4% of European pregnant women use antidepressant treatment, most commonly selective serotonin reuptake inhibitors (SSRIs). Poor pregnancy outcome...

    Authors: Åsa Edvinsson, Charlotte Hellgren, Theodora Kunovac Kallak, Helena Åkerud, Alkistis Skalkidou, Elisabet Stener-Victorin, Romina Fornes, Olav Spigset, Susanne Lager, Jocelien Olivier and Inger Sundström-Poromaa

    Citation: BMC Pregnancy and Childbirth 2019 19:479

    Content type: Research article

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  22. Gestational diabetes mellitus (GDM) exposes mothers and their offspring to short and long-term complications. The objective of this study was to identify the importance of potentially modifiable predictors of ...

    Authors: Maria-Christina Antoniou, Leah Gilbert, Justine Gross, Jean-Benoît Rossel, Céline J. Fischer Fumeaux, Yvan Vial and Jardena J. Puder

    Citation: BMC Pregnancy and Childbirth 2019 19:469

    Content type: Research article

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  23. Pravastatin, a known inducer of endothelial nitric-oxide synthase (eNOS) was demonstrated in human placenta, however the exact mechanism of it’s action is not fully understood. Since placental NO (nitric oxide...

    Authors: Zita Pánczél, Zoltán Kukor, Dorina Supák, Bence Kovács, András Kecskeméti, Rita Czizel, Magdolna Djurecz, Bálint Alasztics, Krisztián Benedek Csomó, András Hrabák and Sándor Valent

    Citation: BMC Pregnancy and Childbirth 2019 19:426

    Content type: Research article

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  24. It is still uncertain whether surgical evacuation adversely affects subsequent embryo transfer. The present study aims to assess the influence of surgical evacuation on the pregnancy outcomes of subsequent emb...

    Authors: Junan Meng, Mengchen Zhu, Wenjuan Shen, Xiaomin Huang, Haixiang Sun and Jianjun Zhou

    Citation: BMC Pregnancy and Childbirth 2019 19:409

    Content type: Research article

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  25. In Uruguay it is mandatory to review all cases of positive HIV or reactive syphilis tests in pregnancy and peripartum. We compared the rates of mother-to-child transmission of syphilis and HIV detected by case...

    Authors: Susana Cabrera, Mariangela Freitas Silveira, Ana Visconti, Fabian García, Rafael Aguirre, Rodolfo Gomez Ponce de Leon, Jorge Quian and Suzanne J. Serruya

    Citation: BMC Pregnancy and Childbirth 2019 19:400

    Content type: Research article

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  26. Vitamin D plays an important role in human physiology and pathology. The receptor for vitamin D regulates 0.5–5% of the human genome. Accordingly, vitamin D insufficiency has been shown to increase the risk of...

    Authors: Alessio Paffoni, Edgardo Somigliana, Veronica Sarais, Stefania Ferrari, Marco Reschini, Sofia Makieva, Enrico Papaleo and Paola Viganò

    Citation: BMC Pregnancy and Childbirth 2019 19:395

    Content type: Study protocol

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  27. Breast stimulation is performed to self-induce labor. However, there are apparently no reports on hormonal evaluation during stimulation for consecutive days in relation to induction effect. We evaluated the s...

    Authors: Kaori Takahata, Shigeko Horiuchi, Yuriko Tadokoro, Erika Sawano and Kazuyuki Shinohara

    Citation: BMC Pregnancy and Childbirth 2019 19:351

    Content type: Research article

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  28. Preeclampsia is a major cause of maternal, fetal and neonatal morbidity and mortality, particularly in developing countries. Considering the burden of preeclampsia and its associated complications, it is impor...

    Authors: Nisha S. Wadhwani, Deepali P. Sundrani, Girija N. Wagh, Savita S. Mehendale, Manish M. Tipnis, Priscilla C. Joshi, Arun S. Kinare, Sanjay K. Lalwani, Narayanan S. Mani, Nomita Chandhiok, Giriraj R. Chandak, Sanjay A. Gupte, Caroline H. D. Fall and Sadhana R. Joshi

    Citation: BMC Pregnancy and Childbirth 2019 19:308

    Content type: Study protocol

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  29. Recent evidence suggests early screening of preeclampsia and small-for-gestational-age (SGA) would benefit pregnancies followed by subsequent prophylactic use of aspirin. Multi-marker models have shown capabil...

    Authors: Jing Zhang, Luhao Han, Wei Li, Qiaobin Chen, Jie Lei, Min Long, Weibin Yang, Wenya Li, Lizhen Zeng and Sifan Zeng

    Citation: BMC Pregnancy and Childbirth 2019 19:304

    Content type: Research article

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  30. Gestational diabetes mellitus (GDM) is a big health problem that adversely affects both the maternal and perinatal outcomes. We aimed to predict the development of GDM in the first trimester using high sensiti...

    Authors: Warda Naser, Ishag Adam, Duria A. Rayis, Mohammed A. Ahmed and Hamdan Z. Hamdan

    Citation: BMC Pregnancy and Childbirth 2019 19:301

    Content type: Research article

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  31. Oxytocin is a key hormone in childbirth, and synthetic oxytocin is widely administered to induce or speed labour. Due to lack of synthetized knowledge, we conducted a systematic review of maternal plasma level...

    Authors: Kerstin Uvnäs-Moberg, Anette Ekström-Bergström, Marie Berg, Sarah Buckley, Zada Pajalic, Eleni Hadjigeorgiou, Alicja Kotłowska, Luise Lengler, Bogumila Kielbratowska, Fatima Leon-Larios, Claudia Meier Magistretti, Soo Downe, Bengt Lindström and Anna Dencker

    Citation: BMC Pregnancy and Childbirth 2019 19:285

    Content type: Research article

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  32. The prediction of preterm birth (PTB) is important in the management of symptomatic preterm labour women. We evaluated the effectiveness of the foetal fibronectin (fFN) test for predicting PTB in symptomatic p...

    Authors: Soo Yeun Jun, Ji Young Lee, Hyun-Mi Kim, Mi Ju Kim, Hyun-Hwa Cha and Won Joon Seong

    Citation: BMC Pregnancy and Childbirth 2019 19:241

    Content type: Technical advance

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  33. We examined whether inferior thyroid artery peak systolic velocity (ITA-PSV) predicts an increase in levothyroxine (LT4) dosage in pregnant women with Hashimoto’s thyroiditis.

    Authors: Masafumi Kurajoh, Akiyo Yamasaki, Toshiki Nagasaki, Yuki Nagata, Shinsuke Yamada, Yasuo Imanishi, Masanori Emoto, Kanae Takahashi, Kouji Yamamoto, Ayumi Shintani and Masaaki Inaba

    Citation: BMC Pregnancy and Childbirth 2019 19:232

    Content type: Research article

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  34. Early life microflora is an important determinant of immune and metabolic development and may have lasting consequences. However, the mode of delivery and the effect of povidone iodine disinfection on neonatal...

    Authors: Hongping Li, Shaoyun Chen, Lijuan Wu, Huilin Wang, Kelin Xiao, Yanling Gao, Yao Li, Huiqin Li, Bin Xiao and Yuanfang Zhu

    Citation: BMC Pregnancy and Childbirth 2019 19:213

    Content type: Research article

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  35. Children born after intracytoplasmic sperm injection (ICSI) are at increased risk of specific major birth defects compared with children born after in vitro fertilization (IVF). However, whether this risk is d...

    Authors: Seung Chik Jwa, Junna Jwa, Akira Kuwahara, Minoru Irahara, Osamu Ishihara and Hidekazu Saito

    Citation: BMC Pregnancy and Childbirth 2019 19:192

    Content type: Research article

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  36. Preeclampsia is associated with chronic inflammation. The cholinergic anti-inflammatory pathway regulates systemic inflammation through activating α7 nicotinic acetylcholine receptors (α7nAChR) expressed in mo...

    Authors: Hongmei Xu, Qingyang Shi, Yanxiang Mo, Linlin Wu, Jishuang Gu and Ying Xu

    Citation: BMC Pregnancy and Childbirth 2019 19:188

    Content type: Research article

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  37. Tubal pregnancy is recognized as one of the most common ectopic pregnancy types. Salpingitis may result in tubal pregnancy by causing fallopian tube occlusion and hydrosalpinx. B cell activation factor (BAFF) ...

    Authors: Jianying Xu, Xingguang Luo, Shihao Qu, Guiyan Yang and Nianchun Shen

    Citation: BMC Pregnancy and Childbirth 2019 19:169

    Content type: Research article

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  38. Vitamin D deficiency is a growing public health problem, with pregnant women being particularly vulnerable due to its influences on maternal and neonatal outcomes. However, there are limited data published abo...

    Authors: Natalie L. Burke, Emily W. Harville, Jeffrey K. Wickliffe, Arti Shankar, Maureen Y. Lichtveld and Michael L. McCaskill

    Citation: BMC Pregnancy and Childbirth 2019 19:111

    Content type: Research article

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  39. Takotsubo cardiomyopathy is rare in pregnancy and is characterized by left ventricular dysfunction with apical ballooning. This transient cardiac dysfunction may affect women of childbearing age in the antepar...

    Authors: Felix Mwembi Oindi, Evan Sequeira, Herman Ryan Sequeira and Steve Kyende Mutiso

    Citation: BMC Pregnancy and Childbirth 2019 19:89

    Content type: Case report

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  40. Maternal caffeine intake has repeatedly been linked to babies being born small for gestational age (SGA). SGA babies are known to be at increased risk for adverse neonatal outcomes. The aim of this study was t...

    Authors: Dominika Modzelewska, Rino Bellocco, Anders Elfvin, Anne Lise Brantsæter, Helle Margrete Meltzer, Bo Jacobsson and Verena Sengpiel

    Citation: BMC Pregnancy and Childbirth 2019 19:80

    Content type: Research article

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  41. The determination of foetal Rhesus D (RHD) status allows appropriate use of IgRh prophylaxis by restricting its use to cases of RHD feto-maternal incompatibilities. There is a degree of uncertainty about the c...

    Authors: Meryl Darlington, Bruno Carbonne, Agnès Mailloux, Yves Brossard, Annie Levy-Mozziconacci, Anne Cortey, Hassani Maoulida, Tabassome Simon, Alexandra Rousseau and Isabelle Durand-Zaleski

    Citation: BMC Pregnancy and Childbirth 2018 18:496

    Content type: Research article

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  42. Fetal growth restriction is a disorder of placental dysfunction with three to four-fold increased risk of stillbirth. Fetal growth restriction has pathophysiological features in common with preeclampsia. We hy...

    Authors: Teresa M. MacDonald, Chuong Tran, Tu’uhevaha J. Kaitu’u-Lino, Shaun P. Brennecke, Richard J. Hiscock, Lisa Hui, Kirsten M. Dane, Anna L. Middleton, Ping Cannon, Susan P. Walker and Stephen Tong

    Citation: BMC Pregnancy and Childbirth 2018 18:354

    Content type: Research article

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  43. Choosing the optimal season for conception is a part of family planning since it can positively influence the pregnancy outcome. Changes in the monthly number of infants born with a birth defect can signal pre...

    Authors: Miroslav Peterka, Zbynek Likovsky, Ales Panczak and Renata Peterkova

    Citation: BMC Pregnancy and Childbirth 2018 18:348

    Content type: Research article

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  44. We previously reported that fetal plasma erythropoietin (EPO) concentrations are significantly increased in growth-restricted fetuses with abnormal umbilical artery (UA) Doppler. During hypoxia in an ovine mod...

    Authors: Yao-Lung Chang, An-Shine Chao, Hsiu-Huei Peng, Shuenn-Dyh Chang, Kuan-Ju Chen, Po-Jen Cheng and Tzu-Hao Wang

    Citation: BMC Pregnancy and Childbirth 2018 18:321

    Content type: Research article

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  45. The proportion of hyperglycosylated human chorionic gonadotropin (hCG-h) to total human chorionic gonadotropin (%hCG-h) during the first trimester is a promising biomarker for prediction of early-onset pre-ecl...

    Authors: Katja Murtoniemi, Pia M. Villa, Jaakko Matomäki, Elina Keikkala, Piia Vuorela, Esa Hämäläinen, Eero Kajantie, Anu-Katriina Pesonen, Katri Räikkönen, Pekka Taipale, Ulf-Håkan Stenman and Hannele Laivuori

    Citation: BMC Pregnancy and Childbirth 2018 18:279

    Content type: Research article

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  46. Single nucleotide polymorphism of the follicle-stimulating hormone (FSH) receptor (FSHR) is an important marker of ovarian function. However, its role in female fecundity remains debatable. The aim of the stud...

    Authors: Birute Zilaitiene, Marius Dirzauskas, Rasa Verkauskiene, Rytas Ostrauskas, Joerg Gromoll and Eberhard Nieschlag

    Citation: BMC Pregnancy and Childbirth 2018 18:272

    Content type: Research article

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  47. High parity is associated with greater cardiovascular disease (CVD) among mid-life and older women. Prospective studies of arterial change throughout pregnancy are needed to provide insight into potential mech...

    Authors: Nancy Anderson Niemczyk, Marianne Bertolet, Janet M. Catov, Mansi Desai, Candace K. McClure, James M. Roberts, Akira Sekikawa, Ping Guo Tepper and Emma J. Barinas-Mitchell

    Citation: BMC Pregnancy and Childbirth 2018 18:195

    Content type: Research article

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