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Table 1 Severe perinatal complications in cases of large placental chorioangiomas

From: Placental chorioangioma and pregnancy outcome: a ten-year retrospective study in a tertiary referral centre

Case

GA at delivery/weeks

Maternal complications

Fetal complications

Pregnancy/Children Outcome

1

Singleton

32+ 3

Mirror syndrome, Polyhydramnios

Fetal hydrops

Iatrogenic lethal induction of labor

2

Twin pregnancy

34+ 3

-

Fetal cardiomegaly, Fetal hydrops, Fetal distress, PTB

NICU admission (7 days/28 days), Normal development

3

Singleton

33+ 6

PPROM

Fetal cardiomegaly (transplacental digoxin intervention), Fetal anemia, PTB

NICU admission (13 days), NIH (grade III), Normal development

4

Singleton

25+ 4

Polyhydramnios

Fetal cardiomegaly, Fetal hydrops

Patient asked for lethal induction of labor

5

Singleton

25

-

Fetal cardiomegaly, Fetal hydrops, Fetal anemia, IUD

 

6

Singleton

28+ 4

Polyhydramnios, PPROM

PTB

Stillbirth during labor

11

Singleton

28+ 4

Polyhydramnios, PPROM

Fetal hydrops, Fetal anemia, PTB

NICU admission (61 days), NIH (grade II) and secondary hydrocephalus, Poor performance of left-hand fine motor functions

15

Singleton

27+ 2

Polyhydramnios (amnioreduction intervention),

PTB

Stillbirth during labor

18

Singleton

29+ 4

Polyhydramnios

PTB

NICU admission (46 days), NIH (grade IV), Claudication of the left lower extremity, BPD, infantile cutaneous hemangioma, Transient renal function damage

19

Twin pregnancy

31+ 5

Polyhydramnios, PPROM, Placental abruption

PTB

NICU admission (36 days/32 days), Normal development

21

Singleton

29+ 3

Polyhydramnios, PPROM and chorioamnionitis

Fetal anemia, PTB

NICU admission (2 days), Neonatal shock, NND

23

Singleton

38+ 2

Polyhydramnios (amnioreduction and oral indomethacin intervention)

-

Normal development

24

Singleton

38+ 1

-

IUD

 

28

Singleton

33+ 3

Polyhydramnios, PPROM, PPH

Fetal hydrops, fetal abnormality

Iatrogenic lethal induction of labor

42

Singleton

37

Polyhydramnios

IUD

 
  1. * GA: gestational age; PTB: preterm birth; NICU: neonatal intensive care unit; PPROM: preterm premature rupture of membrane; NIH: neonatal intracranial hemorrhage; IUD: intrauterine death; NND: neonatal death; BPD: bronchopulmonary dysplasia; PPH: postpartum hemorrhage.