Outcomes | Populations | Model 1 | Model 2 | Model 3 | Distribution-of-the-product (95% CI) | Indirect Effect (95% CI) | Percentage Mediated (%) |
---|---|---|---|---|---|---|---|
OR (95% CI) | OR1 (95% CI) | OR2 (95% CI) | |||||
Adverse neonatal outcomes | Total | 1.45 (1.42–1.49) | 1.47 (1.43–1.51) | 1.43 (1.39–1.47) | 0.31 (0.28–0.34) | 1.37 (1.33–1.41) | 8.51 |
Age < 35 years | 1.43 (1.37–1.49) | 1.59 (1.52–1.66) | 1.55 (1.48–1.61) | 0.32 (0.28–0.37) | 1.38 (1.32–1.45) | 6.78 | |
Age ≥ 35 years | 1.34 (1.29–1.39) | 1.42 (1.37–1.47) | 1.37 (1.33–1.42) | 0.37 (0.33–0.41) | 1.44 (1.39–1.50) | 11.90 | |
Primipara | 1.41 (1.37–1.46) | 1.42 (1.37–1.47) | 1.37 (1.32–1.42) | 0.31 (0.28–0.35) | 1.37 (1.32–1.42) | 11.90 | |
Multipara | 1.41 (1.36–1.47) | 1.53 (1.47–1.60) | 1.49 (1.43–1.56) | 0.38 (0.32–0.43) | 1.46 (1.38–1.54) | 7.55 | |
Low birth weight | Total | 1.24 (1.19–1.30) | 1.24 (1.19–1.30) | 1.17 (1.12–1.23) | 0.45 (0.41–0.50) | 1.57 (1.51–1.64) | 29.17 |
Age < 35 years | 1.20 (1.12–1.29) | 1.36 (1.26–1.45) | 1.29 (1.20–1.38) | 0.47 (0.40–0.54) | 1.60 (1.49–1.71) | 19.44 | |
Age ≥ 35 years | 1.20 (1.13–1.27) | 1.21 (1.14–1.28) | 1.14 (1.08–1.21) | 0.51 (0.46–0.57) | 1.67 (1.58–1.77) | 33.33 | |
Primipara | 1.17 (1.11–1.23) | 1.19 (1.13–1.26) | 1.12 (1.06–1.19) | 0.46 (0.41–0.51) | 1.58 (1.50–1.67) | 36.84 | |
Multipara | 1.15 (1.07–1.24) | 1.30 (1.21–1.40) | 1.24 (1.15–1.34) | 0.53 (0.46–0.60) | 1.70 (1.58–1.83) | 20.00 | |
Premature birth | Total | 1.48 (1.44–1.53) | 1.64 (1.58–1.69) | 1.58 (1.53–1.64) | 0.33 (0.30–0.37) | 1.40 (1.35–1.44) | 9.37 |
Age < 35 years | 1.41 (1.34–1.49) | 1.77 (1.68–1.86) | 1.71 (1.62–1.81) | 0.35 (0.30–0.40) | 1.41 (1.34–1.48) | 7.79 | |
Age ≥ 35 years | 1.34 (1.29–1.39) | 1.56 (1.50–1.63) | 1.50 (1.44–1.57) | 0.38 (0.34–0.43) | 1.47 (1.41–1.53) | 10.71 | |
Primipara | 1.50 (1.43–1.56) | 1.58 (1.51–1.65) | 1.52 (1.45–1.59) | 0.35 (0.31–0.39) | 1.42 (1.36–1.48) | 10.34 | |
Multipara | 1.52 (1.45–1.59) | 1.71 (1.63–1.79) | 1.66 (1.58–1.74) | 0.38 (0.33–0.43) | 1.46 (1.39–1.54) | 7.04 | |
NICU admission | Total | 1.60 (1.55–1.66) | 1.41 (1.36–1.46) | 1.36 (1.32–1.41) | 0.30 (0.27–0.33) | 1.35 (1.31–1.38) | 12.20 |
Age < 35 years | 1.60 (1.51–1.68) | 1.53 (1.44–1.61) | 1.48 (1.40–1.56) | 0.30 (0.26–0.35) | 1.36 (1.30–1.42) | 9.43 | |
Age ≥ 35 years | 1.44 (1.38–1.50) | 1.42 (1.36–1.49) | 1.38 (1.31–1.44) | 0.35 (0.31–0.38) | 1.41 (1.36–1.47) | 9.52 | |
Primipara | 1.53 (1.47–1.60) | 1.41 (1.35–1.48) | 1.37 (1.31–1.43) | 0.29 (0.25–0.32) | 1.33 (1.29–1.38) | 9.76 | |
Multipara | 1.48 (1.40–1.57) | 1.39 (1.32–1.48) | 1.35 (1.28–1.43) | 0.37 (0.31–0.42) | 1.44 (1.37–1.52) | 10.26 |