Effect of levothyroxine treatment on fetal growth among women with mild subclinical hypothyroidism and thyroid peroxidase antibody negative: a cohort study

Table 3 Comparison of fetal growth and birth weight Z-scores between the Untreated or Treated mild SCH group and Euthyroid group

	Euthyroid	Untreated mild SCH with TPOAb⁻		Treated mild SCH with TPOAb⁻
	Euthyroid	Adjust β (95%CI) ^a	Adjust P value	Adjust β (95%CI)	Adjust P value
AC	ref	-0.082(-0.181, 0.017)	0.104	-0.162(-0.35, 0.027)	0.092
BPD	ref	-0.015(-0.115, 0.085)	0.773	-0.195(-0.39, 0.000)	0.050
FL	ref	-0.068(-0.164, 0.027)	0.161	-0.046(-0.241, 0.149)	0.647
HC	ref	0.012(-0.086, 0.109)	0.814	-0.223(-0.422, -0.023)	0.029
EFW	ref	-0.059(-0.157, 0.039)	0.237	-0.158(-0.36, 0.044)	0.126
Birth weight	ref	-0.048(-0.169, 0.074)	0.442	-0.06(-0.278, 0.158)	0.590

Abbreviations: AC abdominal circumference, BPD biparietal diameter, FL femur length, HC head circumference, EFW estimate fetal weight
Bold indicated P < 0.05
^aThe adjust model adjusted for the covariates including maternal age, maternal educational level, current employment status, parity, pre-pregnancy BMI, gestational age of thyroid function testing

ISSN: 1471-2393