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Table 3 The maternal and neonatal outcomes between pregnancies with and without thyroid cancer

From: Pregnancy outcomes and neonatal thyroid function in women with thyroid cancer: a retrospective study

Variables

Thyroid cancer

(n = 212)

Control group (n = 35,641)

P value

Gestational weeks of deliveries, weeks

39.0 (38.0, 40.0)

39.4 (38.6, 40.3)

0.816

GWG of all pregnancies, kg

14.0 (10.9, 16.0)

13.0 (9.0, 16.0)

0.012/ <0.001a

GWG of full-term deliveries, kg

14.0 (11.0, 16.3)

13.0 (9.5, 16.0)

0.011/ <0.001a

Late miscarriage, n (% of pregnancies)

2 (0.9%)

4 (0.0%)

0.001

Stillbirth, n (% of pregnancies)

2 (0.9%)

62 (0.2%)

0.055

Preterm deliveries, n (% of pregnancies)

9 (4.2%)

1706 (4.8%)

0.713

Cesarean section, n (% of deliveries)

83 (39.9%)

12,182 (34.2%)

0.086

GDM, n (% of pregnancies)

44 (20.8%)

6188 (17.4%)

0.194

HDP, n (% of pregnancies)

21 (9.9%)

2583 (7.2%)

0.137

Premature rupture of membranes, n (% of pregnancies)

54(25.5%)

10,927 (30.7%)

0.102

Placenta previa, n (% of pregnancies)

3(1.4%)

349 (1.0%)

0.468

Placenta abruption, n (% of pregnancies)

5(2.4%)

522 (1.5%)

0.246

Abnormally invasive placentation, n (% of pregnancies)

4(1.9%)

1006 (2.8%)

0.412

Postpartum hemorrhage, n (% of pregnancies)

46(21.7%)

6918 (19.4%)

0.401

Boy, n (% of deliveries)

105 (49.5%)

18,309 (51.4%)

0.593

Birthweight, g

3365 (3051, 3680)

3370 (3090, 3650)

0.823

Macrosomia, n (% of deliveries)

15 (7.1%)

2542 (7.1%)

0.974

LBW, n (% of deliveries)

9 (4.2%)

1143 (3.2%)

0.393

Neonatal TSH, µIU/mL

1.93 (1.31, 2.91)

1.79 (1.24, 2.67)

0.145

Full-term neonatal TSH, µIU/mL

1.93 (1.31, 2.92)

1.79 (1.24, 2.67)

0.121

Preterm neonatal TSH, µIU/mL

1.53 (1.25, 2.64)

1.86 (1.34, 2.62)

0.726

  1. Abbreviations: GWG, gestational weight gain; GDM, gestational diabetes mellitus; HDP, hypertensive disorders of pregnancy; LBW, low birth weight
  2. a Adjusted for maternal age, pre-pregnancy BMI, and gestational week of delivery