GROUP A PE (n = 79) | GROUP B NO PE (n = 211) | P value | aP value | |
---|---|---|---|---|
Maternal age at first AFLP pregnancy, y, (mean ± SD) | 26.86 ± 3.63 | 27.32 ± 5.37 | 0.38 | 0.11 |
BMI, Kg/m2, (mean ± SD) | 23.71 ± 3.69 | 24.18 ± 3.22 | 0.50 | 0.89 |
Gravidity, (mean ± SD) | 1.71 ± 0.76 | 1.68 ± 0.84 | 0.72 | 0.69 |
Multiparae | 8(10.13%) | 49(23.22%) | 0.01 | 0.50 |
Fetal sex male | 54(68.35%) | 179(84.83%) | < 0.01 | 0.72 |
Gestational age, d, (mean ± SD) | 241.43 ± 16.56 | 256.82 ± 16.54 | 0.78 | 0.10 |
Multiplets | 19(24.05%) | 6(2.84%) | < 0.01 | 0.77 |
Days from symptom onset to hospitalization, d, (mean ± SD) | 9.80 ± 7.05 | 14.89 ± 20.00 | 0.41 | 0.55 |
Days from symptom onset to parturition, d, (mean ± SD) | 10.80 ± 6.22 | 16.26 ± 20.53 | 0.30 | 0.57 |
APACHEII score, (mean ± SD) | 19.75 ± 10.87 | 17.00 ± 9.04 | 0.97 | 0.16 |
Swansea score, (mean ± SD) | 7.86 ± 1.35 | 7.41 ± 1.53 | 0.71 | 0.07 |
Complications | ||||
Hypertension before pregnancy | 2(2.53%) | 5(2.37%) | 0.99 | 0.99 |
Preeclampsia | 15(18.99%) | 39(18.48%) | 0.99 | 0.54 |
Hypothyroidism during pregnancy | 1(1.27%) | 5(2.84%) | 0.68 | 0.32 |
Gestational diabetes | 5(6.33%) | 12(5.69%) | 0.79 | 0.66 |
Encephalopathy | 22(27.85%) | 59(27.96%) | 0.99 | 0.27 |
Infection | 11(13.92%) | 49(23.22%) | 0.10 | 0.25 |
Postpartum Hemorrhage | 8(10.13%) | 31(14.69%) | 0.34 | 0.89 |
HELLP syndrome | 16(20.25%) | 18(8.53%) | 0.01 | 0.67 |
Placenta previa | 17(21.52%) | 16(7.58%) | < 0.01 | 0.56 |
Placental Abruption | 11(13.92%) | 28(13.27%) | 0.85 | 0.76 |
Fetal distress | 33(41.77%) | 97(45.97%) | 0.60 | 0.50 |
Fetal death | 22(27.85%) | 56(26.54%) | 0.88 | 0.72 |
Others | 3(3.80%) | 16(7.58%) | 0.30 | 0.45 |
Lab on first visit (mean ± SD) | ||||
Hemoglobin(g/L) | 112.43 ± 26.66 | 111.86 ± 25.43 | 0.62 | 0.17 |
Platelet (*109/L) | 145.71 ± 81.71 | 140.36 ± 81.99 | 0.99 | 0.09 |
TBil (mmol/L) | 202.03 ± 107.10 | 139.64 ± 94.59 | 0.86 | 0.88 |
DBil (mmol/L) | 175.16 ± 95.80 | 118.44 ± 91.64 | 0.81 | 0.88 |
ALT (IU/L) | 160.86 ± 158.22 | 363.50 ± 748.94 | 0.37 | 0.45 |
PT (s) | 34.57 ± 38.01 | 18.65 ± 6.25 | < 0.01 | 0.39 |
APTT(s) | 53.77 ± 15.23 | 47.78 ± 17.30 | 0.68 | 0.22 |
Prothrombin activity (%) | 41.93 ± 10.06 | 50.91 ± 19.80 | 0.07 | 0.64 |
Scr (umol/L) | 225.14 ± 39.38 | 179.82 ± 82.59 | 0.052 | 0.68 |
BUN (mmol/L) | 8.77 ± 5.82 | 7.06 ± 3.01 | 0.07 | 0.08 |
WBC(*106/L) | 17.45 ± 9.11 | 15.28 ± 5.07 | < 0.01 | 0.10 |
Trioxypurine (μmol/L) | 391.14 ± 144.48 | 350.91 ± 152.23 | 0.63 | 0.69 |
Management | ||||
Bilirubin adsorption | 20(25.32%) | 2(0.95%) | < 0.01 | NA |
CRRT | 66(83.54%) | 41(19.43%) | < 0.01 | NA |
Cesarean section | 77(97.47%) | 190(90.05%) | 0.04 | 0.53 |
Hysterectomy | 13(16.5%) | 21(9.9%) | 0.43 | 0.52 |