Table 2 Ovulation stimulation cycles and outcomes in patients with ROS
case | cycle | Stimulation protocol | Days of Gn stimulation | Gn total dose (IU) | ovulation trigger(IU) | Serum E2 on trigger day (pg/ml) | No. of retrieved oocytes | No. of MII oocytes | The way of fertilization | No. of fertilization | No. of excellent embryo | Result |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | EFLL | 8 | 2400 | u-HCG10000 | 109.1 | 2 | 2 | ICSI | 2 | 2 | Live born after fresh double embryo transfer |
2 | 2 | mild-stimulation | 15 | 4500 | u-HCG10000 | 95.79 | 1 | 1 | ICSI | 0 | 0 | No fertilization |
3 | EFLL | 11 | 3300 | u-HCG10000 | 43.36 | 3 | 0 | ICSI | 2 | 1 | Three MI stage oocytes were obtained, 2 oocytes fertilized after IVM, and finally 2 embryo cryopreserved | |
4 | Natural cycles | 0 | 0 | u-HCG10000 | 142.8 | 0 | NA | NA | 0 | 0 | No oocytes were obtained | |
3 | 5 | PPOS | 15 | 5700 | NA | NA | NA | NA | NA | NA | NA | No follicle growth, cancelled cycle |
6 | EFLL | 20 | 5725 | u-HCG10000 | 77.71 | 1 | 1 | ICSI | 1 | 1 | One embryo cryopreserved | |
7 | PPOS | 8 | 2400 | u-HCG10000 | 69.33 | 0 | NA | NA | 0 | 0 | No oocytes were obtained | |
8 | Natural cycles | 0 | 0 | u-HCG10000 | 99.06 | 0 | NA | NA | 0 | 0 | No oocytes were obtained | |
9 | PPOS | 1 | 300 | u-HCG10000 | 93.59 | 0 | NA | NA | 0 | 0 | No oocytes were obtained | |
10 | EFLL | 27 | 12,026 | u-HCG10000 | 126.9 | 4 | 4 | ICSI | 2 | 2 | Two embryo cryopreserved | |
4 | 11 | EFLL | 19 | 5200 | u-HCG10000 | 219.8 | 3 | 1 | ICSI | 0 | 0 | One MII oocyte was obtained and did not cleavage after ICSI. Two MI oocytes were obtained and immature after IVM |
12 | PPOS | 7 | 1800 | NA | NA | NA | NA | NA | NA | NA | No follicle growth, cancelled cycle | |
13 | Natural cycles | 0 | 0 | u-HCG10000 | 256.1 | 1 | 0 | NA | 0 | 0 | One MI oocyte was obtained and immature after IVM culture | |
14 | mild-stimulation | 7 | 1200 | u-HCG10000 | 323 | 0 | NA | NA | 0 | 0 | No oocytes were obtained | |
5 | 15 | EFLL | 21 | 5700 | 250ug r-hCG + 2000 u-HCG | 362.7 | 4 | 4 | ICSI | 4 | 2 | Live born after fresh double embryo transfer |
6 | 16 | PPOS | 38 | 6750 | NA | NA | NA | NA | NA | NA | NA | No follicle growth, cancelled cycle |