Skip to main content

Table 1 Summary of reported cases of skull base cerebrospinal fluid leakage in pregnancy

From: Spontaneous skull base cerebrospinal fluid leak during pregnancy: a case report and review of the literature

Case

Relevant History

Symptoms

Onset

Treatment

Delivery

Anesthesia

Postpartum

Weinstein et al. 1979 [6]

History of meningitis with CSF rhinorrhea s/p repair 4 years prior

CSF rhinorrhea

3rd trimester

Expectant management

Forceps-assisted vaginal delivery

Epidural

Recurrence of CSF rhinorrhea 2 weeks postpartum, planned surgical repair

Schabel et al. 2002 [7]

Prior endoscopic surgery 11 months prior

CSF rhinorrhea

1st trimester

Expectant management

Elective primary cesarean section

Spinal

Persistent CSF rhinorrhea after delivery, underwent surgical repair at 3 months that was unsuccessful

Schraven et al. 2012 [4]

None

CSF rhinorrhea and ear leakage

1st trimester

Surgical repair during pregnancy

Elective primary cesarean section

Not specified

Asymptomatic at 2-year follow-up

Michelle et al. 2023 (this study)

None

CSF rhinorrhea and severe headaches

1st trimester

Analgesics and bed rest

Elective primary cesarean section

Spinal

Marked improvement in symptoms after delivery, plan to have surgical repair

  1. CSF Cerebrospinal fluid, s/p Status post