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Table 4 Distribution of SNP array results within groups of different classifications

From: Fetal genetic findings by chromosomal microarray analysis and karyotyping for fetal growth restriction without structural malformations at a territory referral center: 10-year experience

Categories

Clinically significant findings (P/LP)

VOUS

LB

Normal

Gestational age

 ≤ 24 weeks (n = 93)

6, 6.5%

3, 3.2%

2, 2.2%

82, 88.2%

25–28 weeks (n = 80)

1, 1.3%

2, 2.5%

1, 1.3%

76, 95.0%

29–32 weeks (n = 81)

4, 4.9%

1, 1.2%

0, 0.0%

76, 93.8%

 > 32 weeks (n = 5)

0, 0.0%

0, 0.0%

0, 0.0%

5, 100%

Ultrasound findings

Isolated FGR (n = 181)

4, 2.2%

1, 0.6%

5, 2.8%

171, 94.5%

FGR with soft markers (n = 63)

6, 9.5%

2, 3.2%

0, 0.0%

55, 87.3%

FGR with nonstructural abnormalities (n = 15)

1, 6.7%

0, 0.0%

1, 6.7%

13, 86.7%

Serological screening

High risk (n = 25)

3, 12.0%

1, 4.0%

1, 4.0%

20, 80.0%

Low risk (n = 82)

0, 0.0%

2, 2.4%

3, 3.7%

77, 93.9%

  1. P pathogenic, LP likely pathogenic, VOUS variants of uncertain significance, LB likely benign