Table 4 The relationship between the presence of antibiotic resistance genes and resistance to different antibiotics
Resistance genes | Antibiotics | No. (%) of isolates with different resistance pattern | P-value | ||
|---|---|---|---|---|---|
Resistant | Intermediate resistant | Susceptible | |||
ermB (n = 100) | Erythromycin | 71 (71) | 13 (13) | 16 (16) | 0.006 |
Clarithromycin | 47 (47) | 11 (11) | 42 (42) | 0.34 | |
Azithromycin | 48 (48) | 23 (23) | 29 (29) | 0.01 | |
Clindamycin | 54 (54) | 4 (4) | 42 (42) | 0.47 | |
mefA/E (n = 8) | Erythromycin | 4 (50) | 2 (25) | 2 (25) | 0.4 |
Clarithromycin | 6 (75) | 0 | 2 (25) | 0.1 | |
Azithromycin | 6 (75) | 2 (25) | 0 | 0.1 | |
Clindamycin | 6 (75) | 0 | 2 (25) | 0.4 | |
ermTR (n = 38) | Erythromycin | 27 (71.05) | 6 (15.78) | 5 (13.15) | 0.49 |
Clarithromycin | 22 (57.89) | 2 (5.26) | 14 (36.84) | 0.1 | |
Azithromycin | 16 (42.1) | 13 (34.21) | 9 (23.68) | 0.08 | |
Clindamycin | 24 (63.15) | 0 | 14 (36.84) | 0.13 | |
TetO (n = 37) | Tetracycline | 37 (100) | – | 0 | 0.05 |
TetM (n = 79) | Tetracycline | 79 (100) | – | 0 | 0.000 |
aph-A3 (n = 20) | Gentamicin | 3 (15) | – | 17 (85) | 0.79 |
Kanamycin | 15 (75) | – | 5 (25) | 0.08 | |