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Table 4 Joint effects of ACEs with recent SLEs on perinatal CAD

From: Joint effects of recent stressful life events and adverse childhood experiences on perinatal comorbid anxiety and depression

Group

Total

N = 1082 (%)

CAD in the first trimester

CAD in the second trimester

CAD in the third trimester

CAD in the postpartum

aOR (95%CI)

aOR (95%CI)

aOR (95%CI)

aOR (95%CI)

No SLE and ACE

576 (53.2)

Reference

Reference

Reference

Reference

Only SLE

303 (28.0)

1.89 (1.07–3.33)**

2.50 (1.16–5.39)**

2.30 (0.98–5.37)

2.37 (1.10–5.11)*

Only ACE

89 (8.2)

2.80 (1.27–6.20)*

2.01 (0.68–5.95)

0.72 (0.15–3.52)

1.30 (0.35–4.80)

SLE and ACE

114 (10.5)

7.47 (3.73–14.95)***

3.12 (1.19–8.20)**

4.09 (1.34–12.43)*

7.36 (3.04–17.79)***

p for trend

-

< 0.001

0.005

0.008

< 0.001

  1. ACEs adverse childhood experiences, SLEs stressful life events, CAD co-morbid anxiety and depression, OR odds ratio, CI confidence interval
  2. *p < 0.05, **p < 0.01, ***p < 0.001, aOR was adjusted for age, marital status, education status, work status, parity, unexpected pregnancy, alcohol use and intervention