Table 2 Associations between recent SLEs and perinatal CAD

First trimester

No depression and anxiety

661 (61.1)

215 (51.6)

446 (67.1)

Reference

Reference

Only depression

31 (2.9)

12 (2.9)

19 (2.9)

1.31 (0.63–2.75)

0.475

1.23 (0.54–2.81)

0.626

Only anxiety

229 (21.1)

98 (23.5)

131 (19.7)

1.55 (1.14–2.11)

0.005

1.73 (1.24–2.42)

0.001

Co-morbidity

161 (14.9)

92 (22.0)

69 (6.3)

2.77 (1.95–3.93)

< 0.001

2.36 (1.47–3.81)

< 0.001

Second trimester

No depression and anxiety

768 (82.9)

267 (76.7)

501 (86.7)

Reference

Reference

Only depression

11 (1.2)

6 (1.7)

5 (0.9)

2.25 (0.68–7.45)

0.183

1.52 (0.41–5.61)

0.529

Only anxiety

97 (10.5)

45 (13.0)

52 (9.0)

1.62 (1.06–2.49)

0.026

1.84 (1.16–2.90)

0.009

Co-morbidity

50 (5.4)

30 (8.6)

20 (3.4)

2.82 (1.57–5.05)

0.001

2.33 (1.21–4.48)

0.011

Third trimester

No depression and anxiety

625 (82.6)

226 (76.4)

399 (86.6)

Reference

Reference

Only depression

15 (2.0)

9 (3.0)

6 (1.3)

2.65 (0.93–7.54)

0.068

2.03 (0.65–6.29)

0.221

Only anxiety

82 (10.8)

41 (13.9)

41 (8.9)

1.77 (1.11–2.80)

0.016

2.12 (1.28–3.52)

0.004

Co-morbidity

35 (4.6)

20 (6.7)

15 (3.2)

2.36 (1.18–4.69)

0.015

2.81 (1.32–6.01)

0.008

Postpartum

No depression and anxiety

568 (82.9)

202 (76.5)

366 (86.9)

Reference

Reference

Only depression

10 (1.5)

3 (1.1)

7 (1.7)

0.78 (0.20–3.04)

0.716

0.45 (0.10–1.95)

0.284

Only anxiety

58 (8.5)

29 (11.0)

29 (6.9)

1.81 (1.05–3.12)

0.032

1.97 (1.10–3.56)

0.024

Co-morbidity

49 (7.1)

30 (11.4)

19 (4.5)

2.86 (1.57–5.21)

0.001

3.23 (1.67–6.23)

< 0.001