Table 4 Comparison between PsA and AS groups regarding laboratory investigations and disease activity at time points of study
Preconception M (SD) | First trimester M (SD) | Second trimester M (SD) | Third trimester M (SD) | P value | |
|---|---|---|---|---|---|
CRP (mg/L) | |||||
PsA group | 6.1 ± 2.1 | 6.9 ± 2.6 | 10.9 ± 4.7 | 9.3 ± 3.2 | 0.371 |
AS group | 8.4 ± 3.3 | 9.1 ± 3.8 | 15.2 ± 5.3 | 15.9 ± 5.5 | 0.526 |
Control group | 1.1 ± 0.6 | 1.3 ± 1.2 | 1.9 ± 1.3 | 2.3 ± 1.4 | 0.152 |
P value | P1 = 0.026* | P1 = 0.015* | P1 = 0.001* | P1 = 0.001* | |
P2 = 0.001* | P2 = 0.001* | P2 = 0.001* | P2 = 0.001* | ||
IL-17A (pg/L) | |||||
PsA group | 12.7 ± 2.4 | 18.1 ± 12.1 | 55.4 ± 31.1 | 34.1 ± 18.1 | 0.073 |
AS group | 9.1 ± 4.3 | 11.5 ± 4.9 | 38.3 ± 24.3 | 28.4 ± 15.6 | 0.126 |
Control group | 3.1 ± 2.1 | 4.2 ± 2.3 | 4.3 ± 2.6 | 3.8 ± 2.2 | 0.635 |
P value | P1 = 0.001* | P1 = 0.001* | P1 = 0.001* | P1 = 0.001* | |
P2 = 0.001* | P2 = 0.001* | P2 = 0.001* | P2 = 0.001* | ||
Disease Activity | |||||
RAPID 3 score | |||||
< 7 | 46 (95.8) | 45 (73.8) | 32 (66.7) | 40 (83.3) | 0.625 |
≥ 7 | 2 (4.2) | 3 (6.2) | 16 (33.3) | 8 (16.7) | 0.152 |
HAQ score | |||||
0–1 | 44 (91.7) | 43 (89.6) | 35 (72.9) | 37 (77.1) | 0.471 |
1.1–3 | 4 (8.3) | 5 (10.4) | 13 (27.1) | 11 (22.9) | 0.138 |