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Fig. 4 | BMC Pregnancy and Childbirth

Fig. 4

From: Yolk sac tumor and dysgerminoma in the left gonad following gonadoblastoma in the right gonad in a 46,XY DSD with a novel SRY missense mutation: a case report

Fig. 4

Histopathology of the left gonad. A A single follicular structure located in the cortex, suggestive of a primitive ovary. B FOXL2 was expressed more strongly at the epithelium of the follicular structure than SOX9 (C). D A few OCT4-positive cells were present in the center of the follicular structure, suggestive of primordial germ cells. E UGT located in the left lower pole of the gonad. F Extensive calcification of the left upper pole prompted the diagnosis of “burn out” gonadoblastoma. G There were a few scattered OCT4-positive cells in the UGT at the left lower pole. H The invasive seminoma. I Yolk sac tumor showing the S-D body. J The neoplastic cells of seminoma exhibited OCT4 positivity as well as that of D2–40 (L). K Yolk sac tumor exhibited AFP positivity

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