Table 2 Costs, consequences, cost-effectiveness, and clinical outcomes for intervention versus standard care treatment for PPH management
|  | TXA + SOC | SOC |
|---|---|---|
Disaggregated societal perspective | ||
  Total costs of PPH management (for an annual cohort of 510915 PPH cases) | INR 3,375,732,060 (USD 48,615,053) | INR 3,314,015,603 (USD 47,726,254) |
  Cost of PPH management (per patient) | INR 6607 (USD 95.15) | INR 6486 (USD 93.41) |
  QALY – undiscounted (per patient) | 44.894 | 44.712 |
  QALY – discounted (per patient) | 20.250 | 20.168 |
  Incremental cost-utility ratio (undiscounted) | INR 663 per QALY gained | |
  Incremental cost-utility ratio (differential discounting) | INR 1470 per QALY gained | |
Health system perspective | ||
  Total costs of PPH management (for an annual cohort of 510915 PPH cases) | INR 3,031,950,662 (USD 43,664,142) | INR 2,954,109,215 (USD 42,543,121) |
  Cost of PPH management (per patient) | INR 5934 (USD 85.48) | INR 5782 (USD 83.27) |
  QALY – undiscounted (per patient) | 44.894 | 44.712 |
  QALY – discounted (per patient) | 20.250 | 20.168 |
  Incremental cost-utility ratio (undiscounted) | INR 836 per QALY gained | |
  Incremental cost-utility ratio (differential discounting) | INR 1854 per QALY gained | |
Clinical outcomes | ||
  Total number of surgeries (for an annual cohort of 510915 PPH cases) | 19,387 (905 averted) | 20,293 |
  Total number of ICU admissions (for an annual cohort of 510915 PPH cases) | 27,181 (655 averted) | 27,836 |
  Total number of maternal deaths (for an annual cohort of 510915 PPH cases) | 13,923 (1990 averted) | 15,913 |