Fig. 6

Correlation of IDO1 expression with SOCS3 expression in chorionic villi (A and B) and decidua (C and D) cultured with low concentrations of IL-6 (0–2 ng/ml) for 24 h, as measured by qRT-PCR. The correlation of the IL-6 concentration added to the cultures with the expression of SOCS3 and IDO1 mRNA in chorionic villi (A) and decidua (C) cultures and the correlation of IDO1 mRNA expression with SOCS3 mRNA expression in chorionic villi (B) and decidua (D) cultured with low concentrations of IL-6 (0–2 ng/ml) were evaluated and analysed. Correlation of IDO1 expression with SOCS3 expression in chorionic villi (E and F) and decidua (G and H) cultured with high concentration of IL-6 (2–100 ng/ml) for 24 h, as measured by qRT-PCR. The correlation of the IL-6 concentration added to the cultures with the expression of SOCS3 and IDO1 mRNA in cultured chorionic villi (E) and decidua (G) and the correlation of IDO1 mRNA expression with SOCS3 mRNA expression in chorionic villi (F) and decidua (H) cultured with high concentrations of IL-6 (2–100 ng/ml) were evaluated and analysed. The data are presented as the mean ± SE of three similar experiments. IDO1, indoleamine 2,3-dioxygenase; SOCS3, suppressors of cytokine signalling 3; IL-6, interleukin-6