Table 1 Parental information about termination according to five prognostic categories. The specific abnormalities are listed for each category

1. Conditions with a good long-term prognosis

107

94

88

13

12

  Micrognathia

< 5

0

  Unilateral cleft lip

8

0

  Diaphragmatic hernia

< 5

< 5

  Coarctation of aorta

< 5

0

  Right aortic arch

< 5

0

  Persistent left superior vena cava

< 5

0

  Other malformation of the tricuspid valve

0

< 5

  Ventricular septal defect

< 5

0

  Double kidney

< 5

0

  Hydronephrosis

36

0

  Renal agenesis unilateral

< 5

0

  Cystic renal dysplasia unilateral

10

0

  Duplication of the renal pelvis

< 5

0

  Omphalocele

0

< 5

  Gastroschisis

6

< 5

  Intestinal atresia

< 5

< 5

  Anal/rectal atresia

< 5

0

  Clubfoot

11

0

  Congenital malformation of female genitalia

< 5

0

2. Conditions with uncertain long-term prognosis

26

8

31

18

69

  Cleft lip-palate/facial cleft bilateral

< 5

< 5

  Pulmonary adenoid malformation

< 5

0

  Transposition of the great arteries

0

< 5

  Common arterial trunk

0

< 5

  Other malformation of aorta

0

< 5

  Tetralogy of Fallot

< 5

< 5

  Amelia of the lower limb

0

< 5

  Pelvic teratoma

0

< 5

  Lymphangioma

0

< 5

  Hygroma/hydrops

0

8

  Short long bones

< 5

0

  Small biometries

< 5

< 5

3. Conditions with poor long-term prognosis

70

< 5

N/A

67

N/A

  Spina bifida

0

13

  Cerebellar hypoplasia

< 5

< 5

  Agenesis of corpus callosum

0

< 5

  Occipital encephalocele

0

< 5

  Congenital hydrocephalus

0

< 5

  Other specified congenital malformations of brain

0

< 5

  Hypoplastic left heart syndrome

0

9

  Hypoplastic right heart syndrome

0

7

  Ebsteins anomaly

0

< 5

  Congenital cardiomyopathy

0

< 5

  Cystic renal dysplasia bilateral

0

< 5

  Autosomal recessive polycystic kidney disease

0

< 5

  Megacystis/urethral valves

0

< 5

  Multiple malformations

< 5

21

4. Conditions with a lethal prognosis

13

4.1

0

0

13

100

  Anencephaly

0

9

  Holoprosencephaly

0

< 5

  Renal agenesis bilateral

0

< 5

5. Conditions with genetic disorders

104

32.5

< 5

N/A

102

N/A

  Aneuploidy

    Trisomy 13

0

10

    Trisomy 18

0

21

    Trisomy 21

0

43

    Triploidy

0

< 5

  Sex chromosomal abnormality

    Klinefelter syndrome

< 5

< 5

    Triple X syndrome

0

< 5

    Turner syndrome

< 5

10

  Monogenic disorder

< 5

< 5

  Copy number variation (pathogenic)

0

10

Total

320

100

107

33

213

67