From: Chromosomal analysis of 262 miscarried conceptuses: a retrospective study
Maternal age | < 35 | ≥ 35 | |||||
---|---|---|---|---|---|---|---|
Cleavage embryo | Blastocyst | P | Cleavage embryo | Blastocyst | P | ||
History of pregnancy loss | Sporadic | 37(80.4%) | 45(68.2%) | 0.15 | 21(72.4%) | 5(27.8%) | 0.003 |
Recurrent | 9(19.6%) | 21(31.8%) | 8(27.6%) | 13(72.2%) | |||
Gestational age (weeks) | < 12 | 42(93.3%) | 63(95.5%) | 0.954 | 27(93.1%) | 17(94.4%) | 1 |
≥ 12 | 3(6.7%) | 3(4.5%) | 2(6.9%) | 1(5.6%) | |||
Abnormality of chromosomes | Yes | 29(63%) | 21(31.8%) | 0.001 | 21(72.4%) | 6(33.3%) | 0.008 |
No | 17(37%) | 45(68.2%) | 8(27.6%) | 12(66.7%) | |||
Type of chromosomal abnormality | No | 17(37%) | 45(68.2%) | 0.0001 | 8(27.6%) | 12(66.7%) | 0.018 |
Structural | 16(34.8%) | 3(4.5%) | 2(6.9%) | 0 | |||
Numerical | 13(28.3%) | 18(27.3%) | 19(65.5%) | 6(33.3%) | |||
Type of structural abnormality | Del | 8(50%) | 1(33.3%) | 0.523 | 0 | 0 | |
Dup | 6(37.5%) | 2(66.7%) | 2 | 0 | |||
Del and Dup | 2(12.5%) | 0 | 0 | 0 |