Table 2 The comparisons of clinical characteristics between various subgroups
From: Chromosomal analysis of 262 miscarried conceptuses: a retrospective study
Type of pregnancy | Maternal age (years) | Type of fertilization | Type of embryo | Stage of embryo | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP | ART | P | < 35 | ≥ 35 | P | IVF | ICSI | P | Fresh embryo transfer | Frozen embryo transfer | P | Cleavage embryo | Blastocyst | P | ||
History of pregnancy loss | Sporadic | 48(50.5%) | 111(66.5%) | 0.011 | 119(62.3%) | 40(56.3%) | 0.38 | 79(68.7%) | 28(71.8%) | 0.716 | 41(77.4%) | 69(62.2%) | 0.053 | 58(77.3%) | 50(59.5%) | 0.016 |
Recurrent | 47(49.5%) | 56(33.5%) | 72(37.7%) | 31(43.7%) | 36(31.3%) | 11(28.2%) | 12(22.6%) | 42(37.8%) | 17(22.7%) | 34(40.5%) | ||||||
Gestational age (weeks) | < 12 | 88(93.6%) | 156(94%) | 0.908 | 176(93.1%) | 68(95.8%) | 0.615 | 107(93.9%) | 39(100%) | 0.254 | 49(94.2%) | 106(95.5%) | 1 | 69(93.2%) | 80(95.2%) | 0.845 |
≥ 12 | 6(6.4%) | 10(6%) | 13(6.9%) | 3(4.2%) | 7(6.1%) | 0 | 3(5.8%) | 5(4.5%) | 5(6.8%) | 4(4.8%) | ||||||
Abnormality of chromosomes | Yes | 55(57.9%) | 83(49.7%) | 0.202 | 94(49.2%) | 44(62%) | 0.066 | 57(49.6%) | 19(48.7%) | 0.927 | 42(79.2%) | 40(36%) | 0.0001 | 50(66.7%) | 27(32.1%) | 0.0001 |
No | 40(42.1%) | 84(50.3%) | 97(50.8%) | 27(38%) | 58(50.4%) | 20(51.3%) | 11(20.8%) | 71(64%) | 25(33.3%) | 57(67.9%) | ||||||
Type of chromosomal abnormality | No | 40(42.1%) | 84(50.3%) | 0.007 | 97(50.8%) | 27(38%) | 0.002 | 58(50.4%) | 20(51.3%) | 0.985 | 11(20.8%) | 71(64%) | 0.0001 | 25(33.3%) | 57(67.9%) | 0.0001 |
Structural | 4(4.2%) | 22(13.2%) | 24(12.6%) | 2 (2.8%) | 16(13.9%) | 5(12.8%) | 14(26.4%) | 8(7.2%) | 18(24%) | 3(3.6%) | ||||||
Numerical | 51(53.7%) | 61(36.5%) | 70(36.6%) | 42(59.2%) | 41(35.7%) | 14(35.9%) | 28(52.8%) | 32(28.8%) | 32(42.7%) | 24(28.6%) | ||||||
Type of structural abnormality | Del | 2(50%) | 10(45.5%) | 0.051 | 12(50%) | 0 | 0.129 | 5(31.3%) | 4(80%) | 0.019 | 4(28.6%) | 6(75%) | 0.068 | 8(44.4%) | 1(33.3%) | 0.626 |
Dup | 0(0%) | 10(45.5%) | 8(33.3%) | 2(100%) | 10(62.5%) | 0 | 8(57.1%) | 2(25%) | 8(44.4%) | 2(66.7%) | ||||||
Del and Dup | 2(50%) | 2(9%) | 4(16.7%) | 0 | 1(6.3%) | 1(20%) | 2(14.3%) | 0 | 2(11.1%) | 0 | ||||||