Clinical features at the time of non-hysteroscopic myomectomy before pregnancy, which affect adverse pregnancy outcomes: a retrospective cohort study

Table 6 Obstetric outcomes according to the interval time between the myomectomy and the pregnancy

	Interval time between myomectomy and pregnancy (<24 months)(N=89)	Interval time between myomectomy and pregnancy (≥24 months)(N=159)	p-value	Unadjusted odds ratio (95% CI)(Reference: <24 months)	p-value	Adjusted odds ratio (95% CI)^a(Reference: <24 months)	p-value
GA at delivery (weeks)*	37.8 ± 2.4	37.7 ± 2.4	0.620
Birthweight (g)*	3027 ± 599	3025 ± 587	0.975
Placental weight (g)*	655 ± 159	726 ± 230	0.011
Preterm birth^†	7 (8.0)	23 (14.6)	0.092	2.14 (0.95-4.81)	0.066	0.99 (0.36-2.76)	0.993
Emergent delivery^†	17 (19.1)	26 (16.5)	0.359	1.58 (0.76-3.27)	0.223	1.67 (0.66-4.18)	0.277
Placental accreta/increta^†	7 (7.9)	6 (3.8)	0.138	0.60 (0.13-2.77)	0.508	0.27 (0.06-1.35)	0.111
Transfusion^†	24 (27.0)	43 (27.0)	0.557	0.96 (0.49-1.87)	0.892	1.13 (0.53-2.42)	0.745
SGA^†	6 (6.7)	9 (5.7)	0.465	1.24 (0.38-4.04)	0.727	1.02 (0.21-4.92)	0.983
NICU admission^†	18 (20.5)	23 (14.6)	0.156	0.92 (0.41-2.06)	0.839	0.50 (0.18-1.35)	0.170
Composite morbidity ^b^†	8 (9.0)	12 (7.5)	0.430	1.49 (0.54-4.07)	0.439	0.56 (0.14-2.20)	0.405

GA Gestational age, SGA Small for gestational age, NICU Neonatal intensive care unit; ^aAll outcomes were adjusted for maternal age, body mass index, method of conception, twin pregnancy, myomectomy method, sum of the diameters of which the three biggest uterine myomas, number of uterine myomas removed, and type of uterine myomas;^bComposite morbidity includes neonatal sepsis, retinopathy of prematurity, patent ductus arteriosus, respiratory distress syndrome, bronchopulmonary dysplasia and necrotizing enterocolitis; *Data given as mean ± SD, ^†Data given as n (%)

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