Clinical features at the time of non-hysteroscopic myomectomy before pregnancy, which affect adverse pregnancy outcomes: a retrospective cohort study

Table 4 Obstetric outcomes according to the sum of the diameters of which the three biggest uterine myomas

	Sum of the diameters of which the three biggest uterine myomas (<15cm)(N=191)	Sum of the diameters of which the three biggest uterine myomas (≥15cm)(N=57)	p-value	Unadjusted odds ratio (95% CI)(Reference: <15cm)	p-value	Adjusted odds ratio (95% CI) ^a(Reference: <15cm)	p-value
GA at delivery (weeks)*	37.7 ± 2.5	37.6 ± 1.9	0.805
Birthweight (g)*	3063 ± 576	2901 ± 625	0.070
Placental weight (g)*	697 ± 204	710 ± 232	0.699
Preterm birth^†	19 (10.1)	11 (19.3)	0.055	2.14 (0.95-4.81)	0.066	2.41 (0.87-6.67)	0.091
Emergent delivery^†	30 (15.8)	13 (22.8)	0.152	1.58 (0.76-3.27)	0.223	1.17 (0.74-3.75)	0.219
Placental accreta/increta^†	11 (5.8)	2 (3.5)	0.391	0.60 (0.13-2.77)	0.508	0.45 (0.09-2.28)	0.332
Transfusion^†	52 (27.2)	15 (26.3)	0.519	0.96 (0.49-1.87)	0.892	0.80 (0.39-1.64)	0.533
SGA^†	11 (5.8)	4 (7.0)	0.466	1.24 (0.38-4.04)	0.727	1.23 (0.33-4.57)	0.754
NICU admission^†	32 (16.9)	9 (15.8)	0.510	0.92 (0.41-2.06)	0.839	0.84 (0.33-2.12)	0.710
Composite morbidity ^b^†	14 (7.3)	6 (10.5)	0.298	1.49 (0.54-4.06)	0.439	1.61 (0.51-5.09)	0.416

GA Gestational age, SGA Small for gestational age, NICU neonatal intensive care unit; ^aAll outcomes were adjusted for maternal age, body mass index, method of conception, twin pregnancy, Interval time between myomectomy and pregnancy, myomectomy method, number of uterine myomas removed, type of uterine myomas;^bComposite morbidity includes neonatal sepsis, retinopathy of prematurity, patent ductus arteriosus, respiratory distress syndrome, bronchopulmonary dysplasia and necrotizing enterocolitis; *Data given as mean ± SD, ^†Data given as n (%)

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