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Table 2 Pregnancy outcomes of women with moderate-severe OHSS and controls

From: Frozen embryo transfer in the menstrual cycle after moderate-severe ovarian hyperstimulation syndrome: a retrospective analysis

Characteristic

OHSS Group (n = 342)

Matched Control (n = 342)

cOR

aOR

(95% CI)

(95% CI)

Biochemical pregnancy rate (%, n)

65.2 (223/342)

68.4 (234/342)

0.95 (0.69-1.30)

0.82 (0.56-1.20)

Clinical pregnancy rate (%, n)

60.2 (206/342)

62.3 (213/342)

0.97 (0.71-1.32)

0.78 (0.54-1.14)

Ectopic pregnancy rate (%, n)

1.9 (4/206)

0.5 (1/213)

5.05 (0.65-45.45)

9.26 (0.50-170.81)

Miscarriage rate (%, n)

12.4 (25/202)

12.7 (27/212)

0.91 (0.51-1.61)

0.99 (0.51-1.96)

Childbirth

138

149

0.90 (0.66-1.22)

0.73 (0.51-1.04)

Pregnancy complication

 GDM (%, n)

0.7 (1/138)

2.0 (3/149)

0.62 (0.15-2.51)

0.84 (0.14-4.91)

 PIH (%, n)

3.6 (5/138)

3.4 (5/149)

1.25 (0.36-4.37)

1.35 (0.32-5.75)

 Placenta previa (%, n)

1.5 (2/138)

1.3 (2/149)

1.25 (0.18-8.94)

202.4 (0.28-146,434.89)

 Premature rupture of membranes (%, n)

3.6 (5/138)

2.0 (3/149)

2.10 (0.50-8.86)

1.35 (0.27-6.76)

 Postpartum hemorrhage (%, n)

0.7 (1/138)

0 (0/149)

5,331,600.14

3.71

 Preterm birth (%, n)

19.6 (27/138)

14.1 (21/149)

1.16 (0.64-2.11)

1.01 (0.51-2.00)

 Cesarean section (%, n)

67.4 (93/138)

68.5 (102/149)

1.03 (0.66-1.60)

0.67 (0.40-1.13)

 Gestational age (weeks)

37.9 ± 2.0

38.2 ± 1.7

0.26(−0.18-0.71)

3.03 (−0.28-6.34)

 Birth weight (g)

3313.5 ± 565.2

3391.7 ± 574.7

108.03(−31.38-247.45)

153.90 (− 120.13-427.93)

 Birth length (cm)

50.1 ± 2.5

50.0 ± 2.7

0.30(−0.28-0.87)

3.37 (−0.57-7.32)

 Neonatal congenital diseases (%, n)

0.7 (1/138)

0.7 (1/149)

1.25 (0.08-20.08)

6.93

 Neonatal death (%, n)

1.5 (2/138)

0 (0/149)

1.07

9.64

 Other neonatal complication (%, n)

2.2 (3/138)

2.0 (3/149)

1.25 (0.25-6.25)

1.87 (0.24-14.80)

  1. Qualitative data are n (%); quantitative data are mean ± SD
  2. CI confidence interval, GDM gestational diabetes mellitus, PIH gestational hypertension, cOR crude odds ratio under univariable, aOR adjusted odds ratio under multivariable, CI confidence interval. Multivariable was adjusted for BMI, basal serum follicle-stimulating hormone, basal serum estradiol2, basal serum prolactin, basal serum luteinising hormone, total gonadotropin dosage, total days of gonadotropin, number of follicles, serum estradiol2 level on trigger day, serum luteinizing hormone, serum progesterone on trigger day, number of retrieved oocytes, number of transplantable embryos, number of high-quality embryos