Table 1 COH characteristics and preimplantation development outcomes in non-AOA and AOA group for total patients

Cycles, n

97

97

Age, year

33.62 ± 5.25

34.84 ± 4.92

COH protocol, n (%)

0.122

 GnRH-agonist protocol

50 (51.55%)

46 (47.42%)

 GnRH-antagonist protocol

38 (39.18%)

36 (37.11%)

 Other unconventional protocol

9 (9.28%)

15 (15.46%)

Gn total dose, IU

2171.55 ± 932.35

2273.33 ± 1018.15

0.379

No. of MII oocytes, n

689

642

Normal fertilization rate, n (%)

503 (73.00%)

422 (65.73%)

0.006*

Multi-PN formation rate, n (%)

19 (2.76%)

22 (3.43%)

0.112

Cleavage rate, n (%)

493 (98.01%)

413 (97.87%)

0.575

Day 3 good quality embryo rate, n (%)

145 (28.83%)

163 (38.63%)

0.034*

Good quality blastocyst formation rate, n (%)

18 (3.58%)

117 (27.73%)

<  0.001*

Utilization rate, n (%)

50.60 (7.34%)

144.65 (22.53%)

<  0.001*