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Table 5 Multivariable logistic regression analysis based on the data from the training cohort

From: Risk prediction models of gestational diabetes mellitus before 16 gestational weeks

Characteristics

Basic model

(n = 2895)

Extended model

(n = 2116)

β-coefficient

p

OR (95%CI)

β-coefficient

p

OR (95%CI)

Age (year)

0.11

 < 0.001

1.11 (1.08–1.14)

0.14

 < 0.001

1.15 (1.11–1.18)

History of GDM, n (%)

      

 No

Reference

  

Reference

  

 Yes

1.92

 < 0.001

6.80 (3.73–13.40)

1.84

 < 0.001

6.27 (3.39–12.56)

Family history of DM, n (%)

   

Not included

  

 No

Reference

     

 Yes

2.36

 < 0.001

10.60 (3.61–39.53)

   

Pre-pregnancy BMI (kg/m2)

0.97

 < 0.001

1.10 (1.07–1.14)

0.10

 < 0.001

1.10 (1.06–1.15)

 WBC (109/L)

0.12

 < 0.001

1.13 (1.08–1.20)

Not included

  

 PLT (109/L)

0.00

0.021

1.00 (1.00–1.00)

Not included

  

MPV (fL)

0.19

 < 0.001

1.21 (1.12–1.31)

0.15

0.004

1.16 (1.05–1.29)

Creatinine (μmol/L)

-0.04

 < 0.001

0.96 (0.95–0.98)

-0.02

 < 0.001

0.98 (0.96–0.99)

Uric acid (μmol/L)

0.00

0.001

1.00 (1.00–1.01)

0.00

0.008

1.00 (1.00–1.00)

FBG (mmol/L)

0.39

 < 0.001

1.47 (1.24–1.75)

0.48

 < 0.001

1.61 (1.33–1.96)

HCT (%),

Not included

  

0.05

0.013

1.05 (1.01–1.10)

ALT (U/L)

Not included

  

0.01

0.014

1.01 (1.00–1.02)

APTT (s)

Not included

  

-0.07

 < 0.001

0.93 (0.90–0.96)

FIB (mg/dL)

Not included

  

0.24

0.009

1.27 (1.06–1.52)

PAPP-A (MoM)

Not included

  

-0.27

0.002

0.76 (0.64–0.90)

  1. Abbreviations: CI Confidence interval, GDM Gestational diabetes mellitus, DM Diabetes mellitus, PCOS Polycystic ovary syndrome, BMI Body mass index, WBC White blood cell count, NEUT Neutrophil percentage, RBC Red blood cell count, HGB Hemoglobin, HCT Hematocrit, PLT Platelet count, MPV Mean platelet volume, ALT Alanine aminotransferase, AST Aspartate aminotransferase, FBG Fasting blood glucose, PT Prothrombin time, APTT Activated partial thromboplastin time, FIB Fibrinogen, PAPP-A Pregnancy associated plasma protein A