Table 1 Clinical characteristics and laboratory biomarkers among the basic population
From: Risk prediction models of gestational diabetes mellitus before 16 gestational weeks
Variable | Training cohort (n = 2026) | Validation cohort (n = 869) | p |
|---|---|---|---|
Age (year) | 30.0 (27.0–32.0) | 30.0 (27.0–32.0) | 0.753 |
Nulliparous, n (%) | Â | Â | 0.443 |
 No | 1254 (61.9) | 524 (39.7) |  |
 Yes | 772 (38.1) | 345 (60.3) |  |
History of GDM, n (%) | Â | Â | 0.276 |
 No | 1934 (95.5) | 838 (96.4) |  |
 Yes | 92 (4.5) | 31 (3.6) |  |
History of macrosomia, n (%) | Â | Â | 0.099 |
 No | 1992 (98.3) | 862 (99.2) |  |
 Yes | 34 (1.7) | 7 (0.8) |  |
History of abnormal pregnancy, n (%) | Â | Â | 0.474 |
 No | 1943 (95.9) | 828 (95.3) |  |
 Yes | 83 (4.1) | 41 (4.7) |  |
Family history of DM, n (%) | Â | Â | 0.709 |
 No | 2000 (98.7) | 860 (99.0) |  |
 Yes | 26 (1.3) | 9 (1.0) |  |
PCOS, n (%) | Â | Â | 0.911 |
 No | 2000 (98.7) | 859 (98.8) |  |
 Yes | 26 (1.3) | 10 (1.2) |  |
Pre–pregnancy BMI (kg/m2) | 20.6 (18.9–22.7) | 20.5 (18.9–22.6) | 0.875 |
WBC (109/L) | 8.9 (7.6–10.4) | 8.8 (7.7–10.1) | 0.420 |
NEUT (%) | 72.3 (68.1–75.9) | 72.1 (68.1–76.0) | 0.881 |
RBC (1012/L) | 4.0 (3.8–4.3) | 4.1 (3.8–4.3) | 0.316 |
HGB (g/L) | 120.5 (114.0–127.0) | 120.4 (114.0–128.0) | 0.872 |
HCT (%) | 36.0 (34.0–37.9) | 36.0 (34.0–38.0) | 0.457 |
PLT (109/L) | 241.5 (207.7–278.7) | 238.5 (205.6–273.0) | 0.277 |
MPV (fL) | 9.6 (8.6–10.4) | 9.5 (8.6–10.4) | 0.977 |
ALT (U/L) | 12.1 (9.2–18.0) | 12.0 (9.5–17.0) | 0.591 |
AST (U/L) | 16.0 (13.5–19.0) | 16.0 (13.6–18.4) | 0.494 |
Creatinine (μmol/L) | 45.7 (41.0–51.0) | 46.0 (41.2–51.4) | 0.283 |
Uric acid (μmol/L) | 239.0 (202.5–278.2) | 233.0 (203.0–270.0) | 0.202 |
FBG (mmol/L) | 4.5 (4.2–4.9) | 4.5 (4.3–4.9) | 0.405 |