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Table 2 Patients in different degree of TBA level

From: The association of serum total bile acid with new-onset hypertension during pregnancy

TBA

No

PE

EOPE

LOPE

Mild PE

Severe PE

  

No. (%)

p valuea

OR (95% CI)

No. (%)

p valuea

OR (95% CI)a

No. (%)

p valuea

OR (95% CI)a

No. (%)

p valueb

OR (95% CI)

No. (%)

p valueb

OR (95% CI)

 < 1.6

865

270 (31.25)

 

1(reference)

112(12.95)

 

1(reference)

158(18.27)

 

1(reference)

147 (54.44)

 

1(reference)

123 (45.56)

 

1(reference)

1.6 to < 4.1

1322

545 (41.26)

 < 0.001

1.82(1.47–2.26)

241(18.23)

0.001

1.62(1.23–2.12)

304(23.0)

0.002

1.45(1.15–1.82)

237 (43.49)

0.002

0.61(0.45–0.83)

308 (56.51)

0.002

1.64(1.2–2.24)

4.1 to < 8.2

361

192 (53.33)

 < 0.001

2.37(1.71–3.28)

93(25.76)

0.001

1.93(1.33–2.81)

99(27.42)

0.004

1.63(1.17–2.28)

74 (38.54)

0.005

0.56(0.38–0.84)

118 (61.46)

0.005

1.78(1.19–2.66)

8.2 to < 10

37

23 (63.89)

0.001

4.63(1.89–11.35)

10(27.03)

0.011

3.46(1.32–9.04)

13(35.14)

0.003

3.75(1.57–8.98)

5 (21.74)

0.007

0.23(0.08–0.67)

18 (78.26)

0.007

4.27(1.48–12.3)

  1. Adjustment for AST, ALT, T bilirubin, TC, TG, ALB, pregestational diabetes, nulliparity and IVF
  2. PE preeclampsia, EOPE early-onset PE, LOPE late-onset PE
  3. aCompared PE patients with non-PE patients in total pregnant women
  4. bCompared mild PE or severe PE with all PE patients