Letrozole-induced endometrial preparation improved the pregnancy outcomes after frozen blastocyst transfer compared to the natural cycle: a retrospective cohort study

Table 5 Multivariate logistic regression analysis of neonatal outcomes after single vitrified-warmed blastocyst transfer in the letrozole-induced cycle

Outcomes	Adjusted odds ratio	95% CI	P-value
Pregnancy complications ^a	1.304	0.844–2.015	0.2313
Hypertensive disorders of pregnancy ^a	0.341	0.089–1.304	0.1162
Gestational diabetes mellitus ^a	1.403	0.400–4.910	0.5960
Preterm premature rupture of membrane ^a	3.314	0.366–29.984	0.2863
Low-lying placenta ^a	0.885	0.219–3.568	0.8642
Placenta previa ^a	1.036	0.418–2.565	0.9383
Placental abruption ^a	1.857	0.167–20.557	0.6137
Caesarean section ^b	0.884	0.690–1.133	0.3321
Preterm delivery (< 37 weeks) ^c	1.058	0.669–1.676	0.8069
Low birth weight (< 2,500 g) ^d	1.023	0.711–1.473	0.8995
Small for gestational age ^e	1.026	0.623–1.689	0.9178
Large for gestational age ^f	0.800	0.606–1.056	0.1163
Birth defect ^g	1.061	0.649–1.735	0.8113

CI confidence interval
Reference: Natural group
^a Confounders: body mass index and twin pregnancy. ^b Confounders: female age, male age, body mass index, previous caesarean section, and twin pregnancy. ^c Confounders: twin pregnancy. ^d Confounders: female age, body mass index, and twin pregnancy. ^e Confounders: body mass index. ^f Confounders: body mass index, developmental speed, morphological grade of inner cell mass, and twin pregnancy. ^g Confounders: morphological grade of inner cell mass

ISSN: 1471-2393