From: Effect of low dose aspirin application during pregnancy on fetal congenital anomalies
LDA group (n = 1,684) | Control group (n = 1,079) | P value | |
---|---|---|---|
Age, median (IQR) years | 32 (29, 35) | 30 (28, 33) | < 0.001 |
BMI, median (IQR) kg/m2 | 21.3 (19.7, 23.0) | 21.3 (19.2, 23.2) | 0.267 |
Nulliparas, n (%) | 1478 (87.8) | 755 (72.0) | < 0.001 |
Number of previous spontaneous abortion, median (IQR) | 2 (0, 3) | 0 (0, 0) | < 0.001 |
History of early miscarriage, n (%) | 1198 (71.1) | 103 (9.5) | < 0.001 |
History of late miscarriage, n (%) | 183 (10.9) | 13 (1.1) | < 0.001 |
History of still birth, n (%) | 86 (5.1) | 8 (0.7) | < 0.001 |
History of fetal congenital anomalies, n (%) | 41 (2.4) | 3 (0.3) | < 0.001 |
Complications | |||
Hypertension, n (%) | 28 (1.7) | 0 | < 0.001 |
Diabetes, n (%) | 3 (0.2) | 0 | 0.427 |
Rheumatic disease, n (%) | 172 (10.2) | 37 (3.4) | < 0.001 |
Thyroid disease, n (%) | 31 (1.8) | 23 (2.1) | 0.59 |