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Table 1 Descriptive characteristicsa

From: Timing and severity of COVID-19 during pregnancy and risk of preterm birth in the International Registry of Coronavirus Exposure in Pregnancy

 

COVID-19 negative

N = 8628

COVID-19 positive

N = 5636

Total

N = 14,264

Enrollmentb

 Prospective

4033 (47%)

4555 (81%)

8588 (60%)

 Retrospective

4595 (53%)

1081 (19%)

5676 (40%)

Prospective enrollees

 Follow-up data

243 (6.0%)

167 (3.7%)

410 (4.8%)

 Weeks past LMP at enrollment (median (IQR))

27 (18, 35)

25 (17, 33)

26 (17, 34)

 Weeks past LMP at symptom onset/test (median (IQR))

21 (12, 30)

19 (10, 27)

20 (11, 28)

 Weeks past LMP at delivery or end of follow-up (median (IQR))

28 (12, 36)

26 (17, 33)

27 (18, 35)

Retrospective enrollees

 Follow-up data

4449 (97%)

1025 (95%)

5474 (96%)

 Weeks past LMP at enrollment (median (IQR))

49 (44, 54)

47 (43, 53)

49 (44, 54)

 Weeks past LMP at symptom onset/test (median (IQR))

38 (37, 39)

34 (28, 38)

38.0 (35.4, 39.3)

 Weeks past LMP at delivery or end of follow-up (median (IQR))

39 (38, 40)

39 (38, 40)

39 (38, 40)

COVID-19 severity

 Negative

8628 (100%)

 

8628 (60%)

 Asymptomatic

 

577 (10%)

577 (4.0%)

 Mild

 

2104 (37%)

2104 (15%)

 Moderate

 

2662 (47%)

2662 (19%)

 Severe

 

293 (5.2%)

293 (2.1%)

COVID-19 diagnosis/test type

 Negative

8628 (100%)

 

8628 (60%)

 Positive by antibodies only

 

531 (9.4%)

531 (3.7%)

 Positive by throat/nose swab

 

4486 (80%)

4486 (31%)

 Positive clinically only

 

619 (11%)

619 (4.3%)

Reason for COVID-19 test

 Symptoms

1234 (14%)

4082 (72%)

5316 (37%)

 Contact tracing/risk zone travel

1703 (20%)

972 (17%)

2675 (19%)

 Surveillance (healthy)

2460 (29%)

224 (4.0%)

2684 (19%)

 Other/none

3230 (37%)

357 (6.3%)

3587 (25%)

Age

31.0 (27.0, 34.0)

30.0 (27.0, 34.0)

31.0 (27.0, 34.0)

Healthcare coverage

6686 (89%)

3702 (85%)

10,388 (87%)

Pre-existing condition

1112 (15%)

482 (12%)

1594 (14%)

Primiparous

3364 (46%)

1699 (42%)

5063 (44%)

Pre-pregnancy BMI (kg/m2)

  < 25

3218 (47%)

1782 (48%)

5000 (47%)

 25–30

1775 (26%)

1023 (28%)

2798 (27%)

  > = 30

1849 (27%)

902 (24%)

2751 (26%)

Continent

 Africa

378 (4.4%)

238 (4.2%)

616 (4.3%)

 Asia

489 (5.7%)

413 (7.3%)

902 (6.3%)

 Europe

3084 (36%)

1310 (23%)

4394 (31%)

 North America

3328 (39%)

1601 (28%)

4929 (35%)

 South America

1347 (16%)

2073 (37%)

3420 (24%)

  1. aDescriptive characteristics of eligible participants in the International Registry of Coronavirus Exposure in Pregnancy who enrolled between June 2020 and July 2021 (n = 14,264)
  2. bProspective enrollment occurred during pregnancy, and retrospective enrollment during the 6 months after the end of pregnancy
  3. COVID-19 Coronavirus disease 2019, LMP Last menstrual period, BMI Body mass index