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Table 3 Risk of preterm delivery for pregnant women with high cortisol during pregnancy

From: Increased risk of preterm delivery with high cortisol during pregnancy is modified by fetal sex: a cohort study

 

Cortisol, nmol/L

Cases (%)

Unadjusted RRa (95% CI)

p

Adjusted RRb (95% CI)

p

All women

 Baseline

≤6.3

34 (5.5)

1

 

1

 

> 6.3

18 (11.3)

2.07 (1.21, 3.58)

0.008

1.96 (1.13, 3.40)

0.017

 28wk

≤8.5

38 (6.4)

1

 

1

 

>  8.5

9 (6.5)

1.02 (0.50, 2.06)

0.958

1.03 (0.46, 2.29)

0.946

Female fetal sex

 Baseline

≤6.3

21 (6.4)

1

 

1

 

> 6.3

7 (8.3)

1.30 (0.57, 2.95)

0.534

1.17 (0.50, 2.74)

0.714

 28 wk

≤8.5

22 (6.8)

1

 

1

 

>  8.5

4 (6.0)

0.87 (0.31, 2.45)

0.800

1.16 (0.35, 3.81)

0.807

Male fetal sex

 Baseline

≤6.3

13 (4.4)

1

 

1

 

> 6.3

11 (14.7)

3.35 (1.56, 7.18)

0.002

3.18 (1.51, 6.71)

0.002

 28 wk

≤8.5

16 (5.8)

1

 

1

 

>  8.5

5 (6.9)

1.19 (0.45, 3.16)

0.715

0.86 (0.26, 2.89)

0.812

  1. aRelative risk
  2. bAdjusted for supplementation group, gestational age at enrollment, parity, maternal age, education, food insecurity, asset index, BMI, fetal sex, twin pregnancy, time between waking and saliva collection, time between last food or drink (except water) and saliva collection, AGP at enrollment, CRP at enrollment