LC/GDM (N = 20) | Con/GDM (N = 80) | Con/Healthy (N = 80) | p-value | |
---|---|---|---|---|
Variable | ||||
 1st trimester of pregnancy | ||||
  Gestational weeks(wk) | 11.98 ± 2.16 | 11.93 ± 1.96 | 12.41 ± 1.53 | 0.222 |
  FBG (mmol/L) | 4.41 ± 0.43 | 4.50 ± 0.35 | 4.57 ± 0.33 | 0.165 |
  HbA1c (%) (mmol/mol) | 5.14 ± 0.46 (33) a | 5.32 ± 0.27 (35) b | 5.19 ± 0.32 (33) |  < 0.05 |
 2nd trimester of pregnancy | ||||
  Gestational weeks(wk) | 25.51 ± 1.11 | 25.28 ± 1.20 | 25.20 ± 1.00 | 0.539 |
  OGTT | ||||
   Fasting (mmol/L) | 4.15 ± 0.45 | 4.19 ± 0.48 | 4.11 ± 0.33 | 0.411 |
   1 h (mmol/L) | 10.4 ± 1.28a | 9.75 ± 0.98b | 7.15 ± 1.16c |  < 0.001 |
   2 h (mmol/L) | 9.12 ± 0.98a | 8.29 ± 1.06b | 6.19 ± 1.01c |  < 0.001 |
  Abnormal values, type | ||||
   Fasting (≥ 5.1 mmol/L [92 mg/dL]) (n, %) | 1 (5) | 5 (6.25) | Reference | 0.064 |
   1 h (≥ 10.0 mmol/L [180 mg/dL) (n, %) | 14 (70) | 43 (53.75) b | Reference |  < 0.001 |
   2 h (≥ 8.5 mmol/L [153 mg/dL) (n, %) | 14 (70) | 49 (61.25) b | Reference |  < 0.001 |
  Abnormal values, n (%) | ||||
   0 | 0(0) | 0(0) | 80(100) |  < 0.001 |
   ≧1(GDM) | 20(100)a | 80(100) b | 0(0) |  < 0.001 |
   1 | 11(55)a | 64(80) b | 0(0)c |  < 0.001 |
   2 | 9(45)a | 15(18.75) b | 0(0)c |  < 0.001 |
   3 | 0(0) | 1(1.25) | 0(0) | 0.556 |
 Higher-1 h-2 h (n, %) | 8 (40)a | 13 (16.25) b | 0 (0)c |  < 0.001 |
 AUC [mmol/(L˙h)] | 17.0 ± 1.13a | 16.0 ± 0.92b | 12.6 ± 1.85c |  < 0.001 |
 HbA1c (%) (mmol/mol) | 4.90 ± 0.30 (30) | 5.05 ± 0.35 (31) b | 4.92 ± 0.26 (30) |  < 0.05 |
 GA (%) | 12.31 ± 1.23a | 13.8 ± 1.59 | 13.49 ± 1.34c |  < 0.001 |
 Insulin treatment, n (%) |  < 0.001 | |||
  Yes | 2 (10) a | 0 (0) | 0 (0) c |  < 0.001 |
 Detectable urinary ketone bodies (n, % of participants) | ||||
  1st trimester of pregnancy | 2 (10) | 2 (2.5) | 5 (6.25) | 0.306 |
  2nd trimester of pregnancy | 5 (25) a | 1 (1.25) | 1 (1.25)c |  < 0.001 |
  3rd trimester of pregnancy | 1 (5) | 1 (1.25) | 6 (7.5) | 0.158 |