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Table 2 Characteristics of children according to the dose of maternal iron supplementation during pregnancy

From: Adapting prenatal iron supplementation to maternal needs results in optimal child neurodevelopment: a follow-up of the ECLIPSES Study

  Stratum 1 (Hb 110–130 g/L)   Stratum 2 (Hb > 130 g/L)
  Intervention (80 mg/d)
(n = 161)
Control
(40 mg/d)
(n = 167)
Intervention
(20 mg/d)
(n = 82)
Control
(40 mg/d)
(n = 93)
Age at assessment, days 47 ± 15 47 ± 13 47 ± 14 47 ± 14
Sex, girl 51.1 [81] 51.6 [83] 45.9 [37] 45.5 [44]
Gestational age, weeks 39.62 (1.51) 39.74 (1.38) 39.61 (1.50) 39.85 (1.30)
Apgar test score ≥ 7 points, % 98.8 [159] 100 [167] 100 [82] 98.9 [92]
Breastfeeding, yes
 At birth 63.9 [98] 68.3 [114] 63.1 [50] 63.6 [60]
 At assessment 54.4 [87] 63.5 [106] 51.2 [41] 56.5 [52]
Neurodevelopment
 Cognitive developmenta 100.81 (8.86) 101.79 (8.55) 101.28 (9.16) 103.28 (8.95)
 Score < 85, % 3.1 [5] 2.4 [4] 3.7 [3] 1.1 [1]
 Language developmenta 96.44 (8.34) 95.92 (8.61) 95.04 (7.35) 97.34 (8.23)
 Score < 85, % 8.0 [13] 10.1 [17] 8.5 [7] 4.3 [4]
Expressive languageb 8.04 (1.39) 8.16 (1.65) 7.88 (1.41) 8.09 (1.78)
 Score < 7, % 9.3 [14] 12.5 [20] 11.0 [9] 16.1 [15]
Receptive languageb 10.71 (2.12) 10.41 (2.17) 10.43 (2.04) 10.98 (2.04)
 Score < 7, % 4.3 [7] 4.2 [7] 2.4 [2] 4.3 [4]
 Motor developmenta 107.27 (12.74) 107.83 (10.27) 107.16 (10.02) 108.08 (11.35)
 Score < 85, % 3.1 [5] 2.4 [4] 2.4 [2] 4.3 [4]
Fine motorb 11.46 (1.98) 11.53 (1.85) 11.39 (1.92) 11.43 (2.09)
 Score < 7, % 0.6 [1] 0.6 [1] 1.2 [1] 2.2 [2]
Gross motorb 11.12 (2.34) 11.00 (2.26) 11.01 (2.34) 11.19 (2.46)
 Score < 7, % 0 [0] 0.6 [1] 0 [0] 0 [0]
  1. Data are expressed in median ± interquartile range, mean (SD) and % [n]
  2. aThe normal score range for BSID-III was 85–115
  3. bThe normal score range for BSID-III was 7–13