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Table 2 Characteristics of children according to the dose of maternal iron supplementation during pregnancy

From: Adapting prenatal iron supplementation to maternal needs results in optimal child neurodevelopment: a follow-up of the ECLIPSES Study

 

Stratum 1 (Hb 110–130 g/L)

 

Stratum 2 (Hb > 130 g/L)

 

Intervention (80 mg/d)

(n = 161)

Control

(40 mg/d)

(n = 167)

Intervention

(20 mg/d)

(n = 82)

Control

(40 mg/d)

(n = 93)

Age at assessment, days

47 ± 15

47 ± 13

47 ± 14

47 ± 14

Sex, girl

51.1 [81]

51.6 [83]

45.9 [37]

45.5 [44]

Gestational age, weeks

39.62 (1.51)

39.74 (1.38)

39.61 (1.50)

39.85 (1.30)

Apgar test score ≥ 7 points, %

98.8 [159]

100 [167]

100 [82]

98.9 [92]

Breastfeeding, yes

 At birth

63.9 [98]

68.3 [114]

63.1 [50]

63.6 [60]

 At assessment

54.4 [87]

63.5 [106]

51.2 [41]

56.5 [52]

Neurodevelopment

 Cognitive developmenta

100.81 (8.86)

101.79 (8.55)

101.28 (9.16)

103.28 (8.95)

 Score < 85, %

3.1 [5]

2.4 [4]

3.7 [3]

1.1 [1]

 Language developmenta

96.44 (8.34)

95.92 (8.61)

95.04 (7.35)

97.34 (8.23)

 Score < 85, %

8.0 [13]

10.1 [17]

8.5 [7]

4.3 [4]

Expressive languageb

8.04 (1.39)

8.16 (1.65)

7.88 (1.41)

8.09 (1.78)

 Score < 7, %

9.3 [14]

12.5 [20]

11.0 [9]

16.1 [15]

Receptive languageb

10.71 (2.12)

10.41 (2.17)

10.43 (2.04)

10.98 (2.04)

 Score < 7, %

4.3 [7]

4.2 [7]

2.4 [2]

4.3 [4]

 Motor developmenta

107.27 (12.74)

107.83 (10.27)

107.16 (10.02)

108.08 (11.35)

 Score < 85, %

3.1 [5]

2.4 [4]

2.4 [2]

4.3 [4]

Fine motorb

11.46 (1.98)

11.53 (1.85)

11.39 (1.92)

11.43 (2.09)

 Score < 7, %

0.6 [1]

0.6 [1]

1.2 [1]

2.2 [2]

Gross motorb

11.12 (2.34)

11.00 (2.26)

11.01 (2.34)

11.19 (2.46)

 Score < 7, %

0 [0]

0.6 [1]

0 [0]

0 [0]

  1. Data are expressed in median ± interquartile range, mean (SD) and % [n]
  2. aThe normal score range for BSID-III was 85–115
  3. bThe normal score range for BSID-III was 7–13