Adapting prenatal iron supplementation to maternal needs results in optimal child neurodevelopment: a follow-up of the ECLIPSES Study

Table 1 Maternal characteristics

	*Stratum* 1 (Hb 110–130 g/L)		*Stratum* 2 (Hb > 130 g/L)
	Intervention (80 mg/d) (n = 161)	Control (40 mg/d) (n = 167)	Intervention (20 mg/d) (n = 82)	Control (40 mg/d) (n = 93)
Baseline
Age, years	31 ± 7	31 ± 7	31 ± 7	32 ± 7
Parity, yes	55.9 [90]	58.7 [98]	47.6 [39]	54.8 [51]
Pregnancy planning, yes	78.9 [127]	81.4 [136]	86.6 [71]	80.6 [75]
Body mass index
Underweight	1.2 [2]	1.2 [2]	2.4 [2]	2.2 [2]
Normal weight	57.8 [93]	64.1 [107]	62.2 [51]	50.5 [47]
Overweight	28.6 [46]	21.6 [36]	19.5 [16]	33.3 [31]
Obesity	12.4 [20]	13.2 [22]	15.9 [13]	14.0 [13]
Smoking, yes	15.6 [25]	12.1 [21]	15.9 [13]	15.1 [14]
Familiar socioeconomical status^a
High	16.8 [27]	22.2 [37]	15.9 [13]	20.4 [19]
Middle	65.8 [106]	67.7 [113]	68.3 [56]	71.0 [66]
Low	17.4 [28]	10.2 [17]	15.9 [13]	8.6 [8]
Ethnicity
White	79.5 [128]	79.6 [133]	86.6 [71]	69.9 [65]
Asian	0.6 [1]	0 [0]	0 [0]	2.2 [2]
Black	2.5 [4]	3.0 [5]	1.2 [1]	0.0 [0]
Arab	6.8 [11]	4.2 [7]	2.4 [2]	8.6 [8]
Latin American	8.7 [14]	10.8 [18]	8.5 [7]	12.9 [12]
Whole pregnancy
Adherence to the Mediterranean diet^a
Low-Middle	64.0 [103]	59.9 [100]	69.5 [57]	67.7 [63]
High	36.0 [58]	40.1 [67]	30.5 [25]	32.3 [30]
Physical activity^a
Low	14.9 [24]	18.0 [30]	18.3 [15]	26.9 [25]
Moderate	55.3 [89]	52.1 [87]	45.1 [37]	36.6 [34]
High	18.0 [29]	12.6 [21]	17.1 [14]	24.7 [23]
Anxiety assessment^b
Trait	18.04 (9.30)	15.19 (8.06)	16.82 (9.85)	14.43 (8.03)
State	18.07 (7.77)	15.41 (6.79)	16.99 (8.03)	15.84 (7.21)
After delivery
Post-partum depression^c	7.58 (5.22)	6.67 (4.78)	6.50 (5.46)	6.44 (4.36)

Data are expressed in mean (SD) for continuous normally distributed variables, median ± interquartile range for continuous non-normally distributed variables, and % [n] for categorical variables
^aFor an explanation of how categories were defined see the Methods section
^bMeasured by STAI questionnaire (score range: 0 to 60 points). Trait means a relatively stable, anxious propensity that characterises individuals with a tendency to perceive situations as threatening. State means a transient emotional state, characterised by subjective, consciously perceived feelings of attention and apprehension and by hyperactivity of the autonomic nervous system
^cMeasured by Edinburg questionnaire (score range: 0 to 30 points)

ISSN: 1471-2393