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Table 3 Hemoglobin, hematocrit, and reticulocyte count ratio in twins in relation to the time of cord clamping

From: Hemoglobin differences in twins are related to the time of cord clamping, not intertwin transfusion – a prospective cohort study

  Twin 1   Twin 2    
HGB (g/dL) median (IQR) HCT (%) median (IQR) Reticulocyte count ratio median (IQR) HGB (g/dL) median (IQR) P (HGB 1st twin vs 2nd twin) HCT (%) median (IQR) P (HCT 1st twin vs 2nd twin) HGB difference > 8 g/dL N (%)
At birth
 DCC + DCC
N = 210
17.9 (16.9–19.4) 52.1 (48.6–56) 1 (0.5–1.4) 18.4 (16.9–19.3) 0.7 52.5 (49.4–55.7) 0.6 1
 DCC + ECC
N = 24
17.3 (15.5–20.2) 49.2 (43.6–56.3) 0.9 (0.4–1.4) 16.6 (14.3–19.3) 0.1 47.8 (41.6–54.9) 0.2 1
 p1 0.6 0.4 0.9 0.04   0.04   1
 ECC + DCC
N = 50
17.7 (16.5–18.8) 50.7 (47.1–54.3) 1.1 (0.6–1.3) 17.7 (16–19.9) 0.7 52 (48.1–56.2) 0.5 0
 p2 0.3 0.4 0.8 0.5   0.8   0.9
 p3 0.8 0.5 0.2 0.2   0.04   0.9
 ECC + ECC
N = 54
17 (15.7–17.8) 48.5 (44.5–50.7) 1 (0.6–1.4) 17.6 (16.1–19.5) 0.3 50.4 (46–55.1) 0.3 1
 p4  < 0.001  < 0.001 0.9 0.4   0.1   1
 p5 0.8 0.7 1 0.2   0.3   1
 p6 0.2 0.1 0.9 0.8   0.3   0.9
24–48 h after delivery
 DCC + DCC 17.4 (16.4–19) 50.4 (46.9–53.6)   17.9 (16.6–19.5) 0.2 51.2 (47.9–55.5) 0.1 1
 DCC + ECC 15.9 (14.4–18.7) 46.2 (41.8–52)   15 (14.2–16.5) 0.08 42.7 (41.3–46.9) 0.1 1
 p1 0.1 0.1    < 0.001    < 0.001   1
 ECC + DCC 16.6 (15.8–19.9) 47.4 (45.9–53.9)   17.5 (16.3–19.2) 0.3 48.4 (47–55.8) 0.2 0
 p2 0.2 0.3   0.9   0.8   0.9
 p3 0.3 0.5    < 0.001    < 0.001   0.9
 ECC + ECC 15.3 (14.4–16) 44.7 (40.7–47)   15.9 (15–19.3) 0.06 45.2 (42.9–52.5) 0.1 1
 p4  < 0.001  < 0.001   0.01   0.04   1
 p5 0.3 0.5   0.2   0.08   1
 p6  < 0.01  < 0.01    < 0.001    < 0.001   0.9
  1. p1 – DCC + DCC vs DCC + ECC
  2. p2 – DCC + DCC vs ECC + DCC
  3. p3 – DCC + ECC vs ECC + DCC
  4. p4 – DCC + DCC vs ECC + ECC
  5. p5 – DCC + ECC vs ECC + ECC
  6. p6 – ECC + DCC vs ECC + ECC
  7. IQR interquartile range, DCC + DCC delayed cord clamping performed in both twins, DCC + ECC delayed cord clamping in the first and early cord clamping in the second twin performed, ECC + DCC early cord clamping in the first and delayed cord clamping in the second twin performed, ECC + ECC early cord clamping performed in both twins, MC monochorionic gestation, DC dichorionic gestation