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Table 2 Associations of thyroid function, blood lipid levels and pre-pregnancy BMI with risk of GDM

From: The interactive effects of pre-pregnancy body mass index, thyroid function, and blood lipid levels on the risk of gestational diabetes mellitus: a crossover analysis

  

Unadjusted OR (95%CI)

Unadjusted P

Adjusted OR (95% CI)

Adjusted P

pre-pregnancy BMIa

 < 23.00 kg/m2

1.000

 

1.000

 

 ≥ 23.00 kg/m2

4.793 (3.418–6.721)

 < 0.001

4.685 (3.329–6.594)

 < 0.001

TGb

 < 2.30 mmol/L

1.000

 

1.000

 

 ≥ 2.30 mmol/L

1.776 (1.315–2.398)

 < 0.001

1.566 (1.139–2.153)

0.006

TCb

 < 6.20 mmol/L

1.000

 

1.000

 

 ≥ 6.20 mmol/L

0.784 (0.582–1.058)

0.112

0.868 (0.633–1.191)

0.382

LDL-Cb

 < 4.10 mmol/L

1.000

 

1.000

 

 ≥ 4.10 mmol/L

0.781 (0.533–1.146)

0.206

0.818 (0.548–1.223)

0.328

TSHb

 < 3.00 mIU/L

1.000

 

1.000

 

 ≥ 3.00 mIU/L

0.904 (0.542–1.510)

0.701

0.998 (0.580–1.718)

0.995

FT3/FT4b

 < 0.502

1.000

 

1.000

 

 ≥ 0.502

4.248 (3.040–5.936)

 < 0.001

3.459 (2.445–4.895)

 < 0.001

  1. aAdjusted for age, history of abortion and gravidity; bAdjusted for age, history of abortion, gravidity and pBMI
  2. P value < 0.05 was considered statistically significant
  3. BMI Body mass index, GDM Gestational diabetes mellitus, TG Triglyceride, TC Total cholesterol, LDL-C Low-density lipoprotein cholesterol, TSH Thyroid stimulating hormone, FT3 Free triiodothyronine, FT4 Free thyroxine