Fig. 1

Analysis Population from the EARLI study. *Outliers are those with out-of-range placental weight and eccentricity measures. Flow chart showing the selection of the study population. 29 mothers withdrew from the study, while 80 did not have placentas collected or measures taken; of remaining 147 participants, 8 did not have placental morphology measurements available; 1 twin was excluded, and 35 children with no outcome data were excluded. Finally, two individuals were excluded as outliers, due to placental weight and eccentricity values out of the plausible range. This yielded a final analytic sample of 101 individuals with any outcome information available, which “floated” across analyses of individual outcomes (range 84–100)