Prepregnancy body mass index, gestational weight gain, and maternal prepartum inflammation in normal pregnancies: findings from a Chinese cohort

Table 4 Adjusted association of tGWG categorized by the IOM recommendation with maternal prepartum CSI and LGI (n = 5476)

	No. prepartum inflammation /total no	RR (95% CI)^a	P
Maternal prepartum CSI (n = 394)^b
Normal tGWG	177/2707	1.00
Inadequate tGWG	104/1446	1.10 (0.88–1.39)	0.404
Excessive tGWG	113/1323	1.18 (0.94–1.48)	0.158
Maternal prepartum LGI (n = 2617)^c
Normal tGWG	1277/2530	1.00
Inadequate tGWG	618/1342	0.91 (0.85–0.98)	0.011
Excessive tGWG	722/1210	1.14 (1.07–1.21)	< 0.001

^aThe multivariable models adjusted for maternal age, parity, pBMI, and gestational length
^bMaternal prepartum CSI was defined as maternal prepartum serum CRP concentration > 10 mg/L
^cMaternal prepartum LGI was defined as maternal prepartum serum CRP concentration ≥ 3.0 and ≤ 10 mg/L. Women with prepartum CSI were excluded
CI Confidence interval, CRP C-Reactive protein, CSI Clinically significant inflammation, IOM Institute of Medicine, LGI Low-grade inflammation, pBMI Prepregnancy body mass index, RR Relative risk, tGWG Gestational weight gain;

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