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Table 1 Comparison of pregnancy outcomes between ART pregnant women and spontaneously conceived women

From: Analysis of the risk of complications during pregnancy in pregnant women with assisted reproductive technology: a retrospective study using registry linkage from 2013 to 2018 in Shanghai, China

Parameter

Full Cohort

P value c

Singletons Only

P value

ARTa (n = 8102)

SCb (n = 8096)

ART (n = 5960)

SC (n = 8005)

Maternal age (years, mean (SD))

32.4 ± 3.6

32.4 ± 3.6

0.997

32.7 ± 3.7

32.4 ± 3.7

< 0.001

Primiparous (No.(%))

7420(91.6)

6013(74.3)

< 0.001

5734(96.2)

6012(75.1)

< 0.001

Single/multiple births (No.(%))

  

< 0.001

/

/

/

single

5960(73.6)

8005(98.9)

twins

2135(26.4)

89(1.1)

triplets

7(0.1)

2(0.0)

Gestational age (wk, mean (SD))

37.7 ± 2.1

38.6 ± 1.5

< 0.001

38.4 ± 1.6

38.6 ± 1.4

< 0.001

< 32 weeks (No.(%))

143(1.8)

43(0.5)

< 0.001

52(0.9)

36(0.4)

0.002

< 37 weeks (No.(%))

1582(19.5)

505(6.2)

< 0.001

415(7.0)

450(5.6)

0.001

Birth weight (g, mean (SD))

3086.3 ± 650.0

3306.0 ± 478.0

< 0.001

3346.8 ± 497.7

3317.7 ± 465.4

< 0.001

< 1500 g (No.(%))

150(1.9)

30(0.4)

< 0.001

39(0.7)

25(0.3)

0.007

< 2500 g (No.(%))

1468(18.1)

374(4.6)

< 0.001

264(4.4)

312(3.9)

< 0.001

≥4000 g (No.(%))

445(5.5)

501(6.2)

0.071

445(7.5)

499(6.2)

0.010

Obstetrical events (No.(%))

 Cesarean section

6183(76.3)

4093(50.6)

< 0.001

4118(69.1)

4005(50.0)

< 0.001

 Placenta previa

558(6.9)

161(2.0)

< 0.001

368(6.2)

159(2.0)

< 0.001

 Hypertensive disorders

1017(12.6)

763(9.4)

< 0.001

578(9.7)

744(9.3)

0.420

 Gestational Diabetes

1806(22.3)

1412(17.4)

< 0.001

1303(21.9)

1389(17.4)

< 0.001

  1. a. ART Assisted reproductive technology
  2. b. SC Spontaneously conceived pregnancy
  3. c. Date are statistically significant at p < 0.05