Table 4 Selected associations of preconception RTIs with adverse pregnancy outcomes, stratifying by infection status

Spontaneous abortion^a

 Trichomoniasis (Independent)

11 /142 (7.75)

3105 /55270 (5.62)

1.41 (0.76–2.62)

1.27 (0.68–2.38)

 Trichomoniasis (Co-infection)

7 /42 (16.67)

3105 /55270 (5.62)

3.36 (1.49–7.57)

3.08 (1.34–7.07)

 Syphilis (Independent)

38 /306 (12.42)

3105 /55270 (5.62)

2.38 (1.70–3.36)

1.95 (1.37–2.76)

 Syphilis (Co-infection)

7 /42 (16.67)

3105 /55270 (5.62)

3.36 (1.49–7.57)

3.11 (1.35–7.18)

Induced abortion / labour due to medical reasons^a

 Syphilis (Independent)

20 /306 (6.54)

1758 /55270 (3.18)

2.13 (1.35–3.36)

1.83 (1.15–2.91)

 Syphilis (Co-infection)

0 /42 (0)

1758 /55270 (3.18)

/

/

Preterm Birth^b

 Syphilis (Independent)

30 /242 (12.40)

3874 /49763 (7.78)

1.68 (1.14–2.46)

1.60 (1.09–2.35)

 Syphilis (Co-infection)

4 /34 (11.76)

3874 /49763 (7.78)

1.59 (0.56–4.50)

1.61 (0.56–4.57)

Very Preterm Birth^b

 Bacterial vaginosis (Independent)

10 /367 (2.72)

731 /49763 (1.47)

1.88 (1.00–3.54)

1.81 (0.96–3.42)

 Bacterial vaginosis (Co-infection)

3 /40 (7.50)

731 /49763 (1.47)

5.44 (1.67–17.68)

5.73 (1.75–18.77)

Macrosomia^b

 Chlamydia (Independent)

11 /99 (11.11)

2061 /49292 (4.18)

2.87 (1.53–5.37)

2.59 (1.38–4.87)

 Chlamydia (Co-infection)

0 /26 (0)

2061 /49292 (4.18)

/

/

 Bacterial vaginosis (Independent)

24 /365 (6.58)

2061 /49292 (4.18)

1.61 (1.06–2.45)

1.54 (1.01–2.34)

 Bacterial vaginosis (Co-infection)

3 /40 (7.50)

2061 /49292 (4.18)

1.86 (0.57–6.03)

1.75 (0.54–5.72)

LGA²

 Bacterial vaginosis (Independent)

49 /365 (13.42)

4967 /49224 (10.09)

1.38 (1.02–1.87)

1.34 (0.99–1.81)

 Bacterial vaginosis (Co-infection)

6 /40 (15.00)

4967 /49224 (10.09)

1.58 (0.66–3.75)

1.55 (0.65–3.72)