Table 2 Fetal anomaly grouping by severity grade and parental decisions to terminate pregnancy
Fetal anomalies | Total (n = 461) N | TOP (n = 264) N (%) |
|---|---|---|
Lethal | 237 | 201 (84.8) |
Anencephaly | 16 | 16 (100) |
Hypoplastic left heart syndrome | 8 | 7 (87.5) |
Multiple cardiac anomalies | 25 | 14 (56) |
Bilateral renal agenesis or severe urinary tract obstruction | 6 | 6 (100) |
Lethal skeletal dysplasia | 9 | 7 (77.8) |
Limb body wall complex | 7 | 7 (100) |
Bart’s hydrops fetalis | 5 | 5 (100) |
Multiple organ defects | 72 | 55 (76.4) |
Chromosomal abnormalities | 79 | 77 (97.5) |
- Trisomy 13 | 11 | 11 (100) |
- Trisomy 18 | 38 | 36 (94.7) |
- Monosomy X with hydrops fetalis | 12 | 12 (100) |
- Other chromosomal abnormalities with multiple anomalies | 18 | 18 (100) |
Others | 10 | 7 (70) |
Potentially lethal | 149 | 59 (39.6) |
Meningocele or encephalocele | 4 | 4 (100) |
Hydrocephalus | 8 | 4 (50) |
Other CNS anomalies | 5 | 3 (60) |
Cardiac defects | 36 | 6 (16.7) |
Congenital diaphragmatic hernia | 7 | 3 (42.9) |
Congenital pulmonary airway malformation | 10 | 0 |
Abdominal wall defects | 16 | 0 |
Urinary tract obstruction with normal amniotic fluid | 4 | 0 |
Non-lethal skeletal dysplasia | 3 | 0 |
Chromosomal abnormalities | 42 | 36 (85.7) |
- Trisomy 21 with major structural anomalies | 31 | 29 (93.6) |
- Other chromosomal abnormalities | 11 | 7 (63.6) |
Others | 14 | 3 (21.4) |
Non-lethal | 75 | 4 (5.3) |
Cleft lip and/or palate | 24 | 0 |
Cystic hygroma | 8 | 1 (12.5) |
Club foot | 3 | 0 |
Ambiguous genitalia | 3 | 0 |
Trisomy 21 alone with minor anomalies | 3 | 3 (100) |
Others | 34 | 0 |