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Table 2 Fetal anomaly grouping by severity grade and parental decisions to terminate pregnancy

From: Factors influencing parental decisions to terminate pregnancies following prenatal diagnoses of major fetal anomalies at Ramathibodi Hospital, Bangkok, Thailand

Fetal anomalies Total (n = 461)
N
TOP (n = 264)
N (%)
Lethal 237 201 (84.8)
Anencephaly 16 16 (100)
Hypoplastic left heart syndrome 8 7 (87.5)
Multiple cardiac anomalies 25 14 (56)
Bilateral renal agenesis or severe urinary tract obstruction 6 6 (100)
Lethal skeletal dysplasia 9 7 (77.8)
Limb body wall complex 7 7 (100)
Bart’s hydrops fetalis 5 5 (100)
Multiple organ defects 72 55 (76.4)
Chromosomal abnormalities 79 77 (97.5)
- Trisomy 13 11 11 (100)
- Trisomy 18 38 36 (94.7)
- Monosomy X with hydrops fetalis 12 12 (100)
- Other chromosomal abnormalities with multiple anomalies 18 18 (100)
Others 10 7 (70)
Potentially lethal 149 59 (39.6)
Meningocele or encephalocele 4 4 (100)
Hydrocephalus 8 4 (50)
Other CNS anomalies 5 3 (60)
Cardiac defects 36 6 (16.7)
Congenital diaphragmatic hernia 7 3 (42.9)
Congenital pulmonary airway malformation 10 0
Abdominal wall defects 16 0
Urinary tract obstruction with normal amniotic fluid 4 0
Non-lethal skeletal dysplasia 3 0
Chromosomal abnormalities 42 36 (85.7)
- Trisomy 21 with major structural anomalies 31 29 (93.6)
- Other chromosomal abnormalities 11 7 (63.6)
Others 14 3 (21.4)
Non-lethal 75 4 (5.3)
Cleft lip and/or palate 24 0
Cystic hygroma 8 1 (12.5)
Club foot 3 0
Ambiguous genitalia 3 0
Trisomy 21 alone with minor anomalies 3 3 (100)
Others 34 0