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Fig. 5 | BMC Pregnancy and Childbirth

Fig. 5

From: Triclosan activates c-Jun/miR-218-1-3p/SLC35C1 signaling to regulate cell viability, migration, invasion and inflammatory response of trophoblast cells in vitro

Fig. 5

TCS suppresses the proliferation and invasion while inducing the inflammatory response of trophoblast cells in vitro via modulation of miR-218-1-3p/SLC35C1 axis. A SLC35C1 expression was tested by RT-qPCR in the Control group, TCS group, TCS + miR-218-1-3p inhibitor group and TCS + miR-218-1-3p inhibitor+sh-SLC35C1#1 group. B-C Cell proliferation and invasion were evaluated in different groups via CCK-8 and transwell assays. D-H RT-qPCR and western blot analyzed the expression of IL-6, IL-1β, TNF-α and CXCL-8 in different groups. The samples in the last group of western blot experiment were indicated positive controls for corresponding antibodies. **P < 0.01

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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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