Skip to main content

Table 3 Correlation between serum miR-200a-3p expression and clinical indicators in HDCP patients

From: High miR-200a-3p expression has high diagnostic values for hypertensive disorders complicating pregnancy and predicts adverse pregnancy outcomes

Parameters

GH (N = 50)

MP (N = 42)

SP (N = 34)

Low EP

High EP

Low EP

High EP

Low EP

High EP

(N = 25)

(N = 25)

(N = 21)

(N = 21)

(N = 17)

(N = 17)

Age (year)

27.9 ± 3.2

29.2 ± 3.1

28.4 ± 3.8

29.0 ± 3.6

27.8 ± 2.5

28.4 ± 4.1

Gestational week

33.6 ± 2.1

33.1 ± 1.3

32.5 ± 2.3

32.5 ± 1.6

33.6 ± 2.9

33.1 ± 1.5

Gravidity (time)

1.6 ± 0.3

1.8 ± 0.4

1.7 ± 0.6

1.7 ± 0.5

1.9 ± 0.5

1.7 ± 0.5

Parity (time)

1.1 ± 0.3

1.0 ± 0.2

1.1 ± 0.3

1.1 ± 0.3

1.1 ± 0.3

1.1 ± 0.2

BMI (kg/m2)

23.3 ± 0.9

26.7 ± 1.3a

23.2 ± 1.1

26.7 ± 1.6b

23.3 ± 1.1

26.8 ± 1.8c

SBP (mmHg)

139.2 ± 4.5

150.5 ± 4.4a

149.8 ± 8.2

168.2 ± 7.5b

162.0 ± 11.5

189.1 ± 11.2c

DBP (mmHg)

89.6 ± 5.4

103.3 ± 5.3a

102.0 ± 7.0

117.8 ± 6.4b

111.6 ± 7.9

130.2 ± 7.7c

PLT (× 109/L)

166.4 ± 17.7

164.4 ± 14.8

135.8 ± 12.8

132.7 ± 13.2

99.5 ± 8.2

79.5 ± 8.5c

S-Cr (umol/L)

67.6 ± 9.7

66.7 ± 9.9

100.6 ± 7.5

97.3 ± 13.9

116.4 ± 6.4

131.5 ± 6.3c

AST (U/L)

40.4 ± 5.6

54.7 ± 5.5a

60.3 ± 5.4

72.5 ± 4.9b

72.8 ± 6.1

87.3 ± 6.0c

ALT (U/L)

28.8 ± 5.9

29.5 ± 6.2

48.5 ± 6.2

46.6 ± 5.2

54.0 ± 4.8

65.2 ± 4.6c

LDH (U/L)

166.4 ± 13.3

162.9 ± 10.3

181.8 ± 15.6

181.4 ± 13.6

198.6 ± 8.8

219.3 ± 8.5c

24-h urine protein (g)

0.17 ± 0.03

0.16 ± 0.03

0.50 ± 0.09

0.69 ± 0.08b

2.33 ± 0.09

3.42 ± 0.40c

Gestational week of delivery (W)

39.0 ± 0.3

38.2 ± 0.3a

38.3 ± 0.4

37.4 ± 0.4b

37.5 ± 0.3

36.8 ± 0.3c

Fetal weight (g)

3767 ± 297

3003 ± 301a

3381 ± 287

2683 ± 310b

3024 ± 297

2303 ± 306c

S/D

2.99 ± 0.22

3.55 ± 0.21a

3.63 ± 0.28

4.26 ± 0.25b

4.19 ± 0.28

4.85 ± 0.27c

FGR

2 (8%)

7 (28%)a

5 (23.8%)

10 (47.6%)b

6 (35.3%)

13 (76.5%)c

  1. BMI Body Mass Index, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, PLT Platelet count, S-Cr Serum Creatinine, AST Aspartate Transaminase, ALT Alanine Transaminase, LDH Lactate Dehydrogenase, S/D Fetal umbilical artery Systolic to Diastolic ratio, FGR Fetal Growth Restriction
  2. The measurement data were expressed as mean ± standard deviation. One-way ANOVA or Chi-square test was used for comparisons between groups.
  3. a Represented in the HG group, miR200a-3p high EP group compared with the low EP group, P < 0.05;
  4. b Represented in the MP group, miR200a-3p high EP group compared with the low EP group, P < 0.05;
  5. c Represented in the SP group, miR200a-3p high EP group compared with the low EP group, P < 0.05