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Table 3 Correlation between serum miR-200a-3p expression and clinical indicators in HDCP patients

From: High miR-200a-3p expression has high diagnostic values for hypertensive disorders complicating pregnancy and predicts adverse pregnancy outcomes

Parameters GH (N = 50) MP (N = 42) SP (N = 34)
Low EP High EP Low EP High EP Low EP High EP
(N = 25) (N = 25) (N = 21) (N = 21) (N = 17) (N = 17)
Age (year) 27.9 ± 3.2 29.2 ± 3.1 28.4 ± 3.8 29.0 ± 3.6 27.8 ± 2.5 28.4 ± 4.1
Gestational week 33.6 ± 2.1 33.1 ± 1.3 32.5 ± 2.3 32.5 ± 1.6 33.6 ± 2.9 33.1 ± 1.5
Gravidity (time) 1.6 ± 0.3 1.8 ± 0.4 1.7 ± 0.6 1.7 ± 0.5 1.9 ± 0.5 1.7 ± 0.5
Parity (time) 1.1 ± 0.3 1.0 ± 0.2 1.1 ± 0.3 1.1 ± 0.3 1.1 ± 0.3 1.1 ± 0.2
BMI (kg/m2) 23.3 ± 0.9 26.7 ± 1.3a 23.2 ± 1.1 26.7 ± 1.6b 23.3 ± 1.1 26.8 ± 1.8c
SBP (mmHg) 139.2 ± 4.5 150.5 ± 4.4a 149.8 ± 8.2 168.2 ± 7.5b 162.0 ± 11.5 189.1 ± 11.2c
DBP (mmHg) 89.6 ± 5.4 103.3 ± 5.3a 102.0 ± 7.0 117.8 ± 6.4b 111.6 ± 7.9 130.2 ± 7.7c
PLT (× 109/L) 166.4 ± 17.7 164.4 ± 14.8 135.8 ± 12.8 132.7 ± 13.2 99.5 ± 8.2 79.5 ± 8.5c
S-Cr (umol/L) 67.6 ± 9.7 66.7 ± 9.9 100.6 ± 7.5 97.3 ± 13.9 116.4 ± 6.4 131.5 ± 6.3c
AST (U/L) 40.4 ± 5.6 54.7 ± 5.5a 60.3 ± 5.4 72.5 ± 4.9b 72.8 ± 6.1 87.3 ± 6.0c
ALT (U/L) 28.8 ± 5.9 29.5 ± 6.2 48.5 ± 6.2 46.6 ± 5.2 54.0 ± 4.8 65.2 ± 4.6c
LDH (U/L) 166.4 ± 13.3 162.9 ± 10.3 181.8 ± 15.6 181.4 ± 13.6 198.6 ± 8.8 219.3 ± 8.5c
24-h urine protein (g) 0.17 ± 0.03 0.16 ± 0.03 0.50 ± 0.09 0.69 ± 0.08b 2.33 ± 0.09 3.42 ± 0.40c
Gestational week of delivery (W) 39.0 ± 0.3 38.2 ± 0.3a 38.3 ± 0.4 37.4 ± 0.4b 37.5 ± 0.3 36.8 ± 0.3c
Fetal weight (g) 3767 ± 297 3003 ± 301a 3381 ± 287 2683 ± 310b 3024 ± 297 2303 ± 306c
S/D 2.99 ± 0.22 3.55 ± 0.21a 3.63 ± 0.28 4.26 ± 0.25b 4.19 ± 0.28 4.85 ± 0.27c
FGR 2 (8%) 7 (28%)a 5 (23.8%) 10 (47.6%)b 6 (35.3%) 13 (76.5%)c
  1. BMI Body Mass Index, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, PLT Platelet count, S-Cr Serum Creatinine, AST Aspartate Transaminase, ALT Alanine Transaminase, LDH Lactate Dehydrogenase, S/D Fetal umbilical artery Systolic to Diastolic ratio, FGR Fetal Growth Restriction
  2. The measurement data were expressed as mean ± standard deviation. One-way ANOVA or Chi-square test was used for comparisons between groups.
  3. a Represented in the HG group, miR200a-3p high EP group compared with the low EP group, P < 0.05;
  4. b Represented in the MP group, miR200a-3p high EP group compared with the low EP group, P < 0.05;
  5. c Represented in the SP group, miR200a-3p high EP group compared with the low EP group, P < 0.05