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Table 3 Adjusted risk ratios and differences between women with no anemia and those with mild, moderate and severe

From: Anemia and adverse outcomes in pregnancy: subgroup analysis of the CLIP cluster-randomized trial in India

 

Unadjusted risk (%)

Risk difference % (95% CI) a

Risk ratio (95% CI) a

E-value point estimate ab

E-value lower bound ab

Blood transfusion

 None

2.5

Reference

Reference

-

-

 Mild

4.1

2.27 (1.29, 3.26)

2.16 (1.31, 3.56)

3.74

1.95

 Moderate

4.5

2.68 (1.77, 3.58)

2.37 (1.56, 3.59)

4.17

2.50

 Severe

11.8

9.20 (3.18, 15.23)

5.70 (3.00, 10.85)

10.9

5.45

Antepartum hemorrhage

 None

1.0

Reference

Reference

-

-

 Mild

1.3

0.22 (-0.54, 0.97)

1.20 (0.63, 2.29)

-

-

 Moderate

0.6

-0.39 (-1.14, 0.36)

0.65 (0.30, 1.39)

-

-

 Severe

1.5

NA abc

NA abc

-

-

Sepsis

 None

1.1

Reference

Reference

-

-

 Mild

1.2

0.01 (-0.69, 0.70)

1.01 (0.62, 1.65)

-

-

 Moderate

1.1

-0.23 (-1.27, 0.82)

0.84 (0.36, 1.94)

-

-

 Severe

0.0

NA abc

NA abc

-

-

Postpartum hemorrhage

 None

0.6

Reference

Reference

-

-

 Mild

0.7

0.15 (-0.23, 0.54)

1.34 (0.60, 3.00)

-

-

 Moderate

0.7

0.24 (-0.13, 0.61)

1.53 (0.69, 3.40)

-

-

 Severe

2.9

1.72 (-0.89, 4.33)

4.82 (1.27, 18.3)

9.11

1.86

Hypertension (POM) abcd

 None

12.4

Reference

Reference

-

-

 Mild

9.2

-3.11 (-4.15, -2.07)

0.75 (0.70, 0.80)

2.00

1.80

 Moderate

8.6

-3.62 (-5.84, -1.39)

0.70 (0.58, 0.85)

2.21

1.63

 Severe

11.1

0.01 (-7.12, 7.13)

1.00 (0.56, 1.79)

-

-

Hypertension (expanded) abcd

 None

21.0

Reference

Reference

-

-

 Mild

15.6

-3.79 (-5.48, -2.1)

0.80 (0.73, 0.88)

1.80

1.53

 Moderate

14.5

-4.35 (-6.24, -2.47)

0.77 (0.70, 0.85)

 

1.63

 Severe

11.1

-7.72 (-13.77, -1.66)

0.60 (0.34, 1.05)

-

-

Pre-eclampsia abcd

 None

8.8

Reference

Reference

-

-

 Mild

6.4

-2.13 (-5.14, 0.89)

0.75 (0.53, 1.07)

-

-

 Moderate

6.0

-2.67 (-4.98, -0.35)

0.69 (0.55, 0.86)

2.25

1.60

 Severe

11.1

3.20 (-1.23, 7.63)

1.37 (1.01, 1.88)

2.08

1.11

Perinatal composite

 None

19.9

Reference

Reference

-

-

 Mild

17.5

-3.56 (-8.19, 1.07)

0.82 (0.65, 1.04)

-

-

 Moderate

16.6

-2.94 (-7.38, 1.49)

0.85 (0.68, 1.07)

-

-

 Severe

29.4

7.51 (-3.37, 18.39)

1.37 (0.89, 2.11)

-

-

  1. a Estimates are adjusted for trial arm, maternal age, nulliparity, body-mass-index, gestational age at enrolment, maternal basic education, husband basic education, multiple pregnancy, and religion
  2. bc Size of association between unmeasured confounder and outcome needed to move the point estimate or lower bound of confidence interval to 1.0 (i.e., compatible with a null effect). Only displayed for those estimates where the lower confidence bound is > 1
  3. def Could not be reliably estimated due to small sample size
  4. ghij Only available for women in the intervention arm with blood pressure measurement
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BMC Pregnancy and Childbirth

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